A brave new world of RNA-binding proteins

MW Hentze, A Castello, T Schwarzl… - Nature reviews Molecular …, 2018 - nature.com
RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …

Exploring the expanding universe of host-virus interactions mediated by viral RNA

A Castello, L Álvarez, W Kamel, L Iselin, J Hennig - Molecular Cell, 2024 - cell.com
RNA is a central molecule in RNA virus biology; however, the interactions that it establishes
with the host cell are only starting to be elucidated. In recent years, a methodology revolution …

Transcriptome-wide discovery of coding and noncoding RNA-binding proteins

R Huang, M Han, L Meng… - Proceedings of the …, 2018 - National Acad Sciences
Transcriptome-wide identification of RNA-binding proteins (RBPs) is a prerequisite for
understanding the posttranscriptional gene regulation networks. However, proteomic …

In planta determination of the mRNA-binding proteome of Arabidopsis etiolated seedlings

M Reichel, Y Liao, M Rettel, C Ragan, M Evers… - The Plant …, 2016 - academic.oup.com
RNA binding proteins (RBPs) control the fate and expression of a transcriptome. Despite this
fundamental importance, our understanding of plant RBPs is rudimentary, being mainly …

SONAR discovers RNA-binding proteins from analysis of large-scale protein-protein interactomes

KW Brannan, W **, SC Huelga, CAS Banks… - Molecular cell, 2016 - cell.com
RNA metabolism is controlled by an expanding, yet incomplete, catalog of RNA-binding
proteins (RBPs), many of which lack characterized RNA binding domains. Approaches to …

Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila

VO Sysoev, B Fischer, CK Frese, I Gupta… - Nature …, 2016 - nature.com
The maternal-to-zygotic transition (MZT) is a process that occurs in animal embryos at the
earliest developmental stages, during which maternally deposited mRNAs and other …

Discovering the RNA-binding proteome of plant leaves with an improved RNA interactome capture method

M Bach-Pages, F Homma, J Kourelis, F Kaschani… - Biomolecules, 2020 - mdpi.com
RNA-binding proteins (RBPs) play a crucial role in regulating RNA function and fate.
However, the full complement of RBPs has only recently begun to be uncovered through …

RBP2GO: a comprehensive pan-species database on RNA-binding proteins, their interactions and functions

M Caudron-Herger, RE Jansen, E Wassmer… - Nucleic acids …, 2021 - academic.oup.com
RNA–protein complexes have emerged as central players in numerous key cellular
processes with significant relevance in health and disease. To further deepen our …

The landscape of RNA binding proteins in mammalian spermatogenesis

Y Li, Y Wang, YQ Tan, Q Yue, Y Guo, R Yan, L Meng… - Science, 2024 - science.org
Despite continuous expansion of the RNA binding protein (RBP) world, there is a lack of
systematic understanding of RBPs in the mammalian testis, which harbors one of the most …

The mRNA-bound proteome of the human malaria parasite Plasmodium falciparum

EM Bunnik, G Batugedara, A Saraf, J Prudhomme… - Genome biology, 2016 - Springer
Background Gene expression is controlled at multiple levels, including transcription,
stability, translation, and degradation. Over the years, it has become apparent that …