This Perspective is a continuation of our analysis of US FDA-approved small-molecule drugs
(1938–2012) containing nitrogen heterocycles. In this study we report drug structure and …

The piperazine moiety is often found in drugs or in bioactive molecules. This widespread
presence is due to different possible roles depending on the position in the molecule and on …

A persistent and severe mental illness called Schizophrenia affects 20 million people
globally. There is not a single component that causes Schizophrenia, according to research …

This review provides comprehensive data on the recent advances in various preparative
methods of carbamides/thiocarbamides possessing oxygen/sulfur donor sites and their …

1-Substituted 1 H-tetrazoles are valuable building blocks in medicinal chemistry; however,
their limited synthetic accessibility constrains their use. A new continuous-flow strategy was …

A convenient method has been developed for symmetrical and un‐symmetrical urea
synthesis by using Carbonyldiimidazole (CDI) and recyclable activated zinc metal. This …

We report herein a facile direct method for the reductive N‐alkylation of amines with
carboxylic esters, using tert‐butylmagnesium chloride (t‐BuMgCl) as a mediator and Red‐Al …

In this review the most important results achieved in the recent 12–15 years are summarized
focusing on the heterogenous catalytic hydrogenations over transition metals (Pd, Pt, Ru …

Template for Electronic Submission to ACS Journals Page 1 Budapest University of
Technology and Economics Faculty of Chemical and Biochemical Engineering George A. Olah …