[HTML][HTML] Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment
The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …
Extrasynaptic NMDA receptors in acute and chronic excitotoxicity: implications for preventive treatments of ischemic stroke and late-onset Alzheimer's disease
SP Yu, MQ Jiang, SS Shim, S Pourkhodadad… - Molecular …, 2023 - Springer
Stroke and late-onset Alzheimer's disease (AD) are risk factors for each other; the
comorbidity of these brain disorders in aging individuals represents a significant challenge …
comorbidity of these brain disorders in aging individuals represents a significant challenge …
[HTML][HTML] Glutamate excitotoxicity: Potential therapeutic target for ischemic stroke
Z Shen, M ** new therapies for TBI. Current treatments for TBI are primarily focused …
Glutamate receptor ion channels: structure, regulation, and function
The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …
Neuroprotection in stroke: the importance of collaboration and reproducibility
Acute ischaemic stroke accounts for 6.5 million deaths per year, and by 2030 will result in
the annual loss of over 200 million disability-adjusted life years globally. There have been …
the annual loss of over 200 million disability-adjusted life years globally. There have been …
Neuroprotection for ischemic stroke: past, present and future
MD Ginsberg - Neuropharmacology, 2008 - Elsevier
Neuroprotection for ischemic stroke refers to strategies, applied singly or in combination, that
antagonize the injurious biochemical and molecular events that eventuate in irreversible …
antagonize the injurious biochemical and molecular events that eventuate in irreversible …
Role of distinct NMDA receptor subtypes at central synapses
SG Cull-Candy, DN Leszkiewicz - Science's STKE, 2004 - science.org
Most excitatory synapses in the brain use the neurotransmitter glutamate to carry impulses
between neurons. During fast transmission, glutamate usually activates a mixture of N …
between neurons. During fast transmission, glutamate usually activates a mixture of N …