Alzheimer's disease (AD) is a neurodegenerative disorder, most cases of which lack a clear
causative event. This has made the disease difficult to characterize and, thus, diagnose …

This review based on the ESC William Harvey Lecture in Basic Science 2022 highlights
recent experimental and translational progress on the therapeutic targeting of the …

Objective The diversity of the tumour microenvironment (TME) of intrahepatic
cholangiocarcinoma (iCCA) has not been comprehensively assessed. We aimed to …

Chemokines are a family of small, highly conserved cytokines that mediate various
biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that …

Cellulose nanomaterials, often called nanocellulose, have created a lot of buzz as a
renewable building block for new materials such as nanocomposites, aerogels and …

Silicate bioceramics have been considered to possess a wide prospect of clinical
application for orthopedic tissue regeneration due to their excellent osteogenesis and …

After decades of research and clinical trials there is still no cure for Alzheimer's disease
(AD). While impaired clearance of amyloid beta (Aβ) peptides is considered as one of the …

CCL4, a CC chemokine, previously known as macrophage inflammatory protein (MIP)-1β,
has diverse effects on various types of immune and nonimmune cells by the virtue of its …

Leukocyte migration into tissues depends on the activity of chemokines that form
concentration gradients to guide leukocytes to a specific site. Interaction of chemokines with …

Chemokines orchestrate leukocyte trafficking and function in health and disease.
Heterophilic interactions between chemokines in a given microenvironment may amplify …