Cardiovascular disease is the leading cause of death in patients with chronic kidney disease
(CKD). As CKD progresses, CKD-specific risk factors, such as disordered mineral …

The vascular endothelium is a dynamic, functionally complex organ, modulating multiple
biological processes, including vascular tone and permeability, inflammatory responses …

Abstract Fibroblast growth factor 23 (FGF23) is a hormone with a central role in the
regulation of phosphate homeostasis. This regulation is accomplished by the coordinated …

Chronic kidney disease (CKD) is a global health epidemic that accelerates cardiovascular
disease, increases risk of infection, and causes anemia and bone disease, among other …

Background Hyperphosphatemia is associated with cardiovascular morbidity and mortality
in patients receiving maintenance dialysis. It is unknown whether combining two therapies …

Cardiovascular disease (CVD) is highly prevalent in the setting of chronic kidney disease
(CKD). Such coexistence of CVD and CKD—the so-called “cardiorenal or renocardiac …

The current focus on cardiovascular research reflects society's concerns regarding the
alarming incidence of cardiac-related diseases and mortality in the industrialized world and …

Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis,
maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as …

Acute and chronic kidney disease are responsible for large healthcare costs worldwide.
During injury, kidney metabolism undergoes profound modifications in order to adapt to …

Background Compelling evidence suggests that calcium/phosphorus homeostasis-related
parameters may be linked to diabetes mellitus and cardiovascular events. However, few …