[HTML][HTML] Clinical trials of stem cell therapy for cerebral ischemic stroke

M Kawabori, H Shichinohe, S Kuroda… - International Journal of …, 2020 - mdpi.com
Despite recent developments in innovative treatment strategies, stroke remains one of the
leading causes of death and disability worldwide. Stem cell therapy is currently attracting …

Efficacy of stem cell-based therapies for stroke

MR Chrostek, EG Fellows, AT Crane, AW Grande… - Brain research, 2019 - Elsevier
Stroke remains a prevalent disease with limited treatment options. Available treatments offer
little in the way of enhancing neurogenesis and recovery. Because of the limitations of …

Intravenous autologous bone marrow mononuclear stem cell therapy for ischemic stroke: a multicentric, randomized trial

K Prasad, A Sharma, A Garg, S Mohanty, S Bhatnagar… - Stroke, 2014 - ahajournals.org
Background and Purpose—Pilot studies have suggested benefit from intravenous
administration of bone marrow mononuclear stem cells (BMSCs) in stroke. We explored the …

Персонализированная медицина: современное состояние и перспективы

ИИ Дедов, АН Тюльпаков, ВП Чехонин… - Вестник Российской …, 2012 - cyberleninka.ru
В обзоре описаны основные тенденции и направления персонализированной
медицины. Они включают предсказание на основе геномных данных вероятности …

Cell based therapies for ischemic stroke: from basic science to bedside

X Liu, R Ye, T Yan, SP Yu, L Wei, G Xu, X Fan… - Progress in …, 2014 - Elsevier
Cell therapy is emerging as a viable therapy to restore neurological function after stroke.
Many types of stem/progenitor cells from different sources have been explored for their …

The dark side of the force–constraints and complications of cell therapies for stroke

J Boltze, A Arnold, P Walczak, J Jolkkonen… - Frontiers in …, 2015 - frontiersin.org
Cell therapies are increasingly recognized as a promising option to augment the limited
therapeutic arsenal available to fight ischemic stroke. During the last two decades …

Allogeneic umbilical cord blood infusion for adults with ischemic stroke: clinical outcomes from a phase I safety study

DT Laskowitz, ER Bennett, RJ Durham… - Stem cells …, 2018 - academic.oup.com
Stroke is a major cause of death and long-term disability, affecting one in six people
worldwide. The only currently available approved pharmacological treatment for ischemic …

Editing a gateway for cell therapy across the blood–brain barrier

B Achón Buil, C Tackenberg, R Rust - Brain, 2023 - academic.oup.com
Stem cell therapy has been shown to improve stroke outcomes in animal models and is
currently advancing towards clinical practice. However, uncertainty remains regarding the …

Revolutionizing stroke recovery: unveiling the promise of stem cell therapy

LD Panos, P Bargiotas, M Arnold… - Drug design …, 2024 - Taylor & Francis
Stem cells, renowned for their unique regenerative capabilities, present significant hope in
treating stroke, a major cause of disability globally. This review offers a detailed analysis of …

Intravenous autologous bone marrow mononuclear cell transplantation for stroke: phase1/2a clinical trial in a homogeneous group of stroke patients

A Taguchi, C Sakai, T Soma, Y Kasahara… - Stem cells and …, 2015 - liebertpub.com
The goal of this clinical trial was to assess the feasibility and safety of transplanting
autologous bone marrow mononuclear cells into patients suffering severe embolic stroke …