Intracellular pH (pH i) has an important role in the maintenance of normal cell function, and
hence this parameter has to be tightly controlled within a narrow range, largely through the …

Spectroscopic (chromogenic, fluorescent, or chemiluminescent) probes have been widely
used in many fields due to their high sensitivity and unrivaled spatiotemporal resolution. This …

Abstract mTOR (mammalian target of rapamycin) signalling and macroautophagy
(henceforth autophagy) regulate numerous pathological and physiological processes …

An MCM-41-type mesoporous silica nanoparticle (MSN) material with a large average pore
diameter (5.4 nm) is synthesized and characterized. The in vitro uptake and release profiles …

The whole picture: Carbon nanodots labeled with two fluorescent dyes have been
developed as a tunable ratiometric pH sensor to measure intracellular pH. The nanosensor …

Activated human T lymphocytes exposed to apoptotic stimuli targeting mitochondria (ie
staurosporine), enter an early, caspase-independent phase of commitment to apoptosis …

Intracellular pH is an important parameter associated with cellular behaviors and
pathological conditions. Quantitative sensing pH and monitoring its changes by near …

Conditions of the tumor microenvironment, such as hypoxia and nutrient starvation, play
critical roles in cancer progression. However, the role of acidic extracellular pH in cancer …

purpose. Oxidative stress is increased in the retina in diabetes, and antioxidants inhibit
activation of caspase-3 and the development of retinopathy. The purpose of this study was to …

Emodin, a natural anthraquinone derivative isolated from Rheum palmatum L., has been
reported to exhibit anti-cancer effect on several human cancers such as liver cancers and …