Common mental disorders such as schizophrenia, bipolar disorder, and severe major
depression are highly heritable, but differ from single-gene (Mendelian) diseases in that they …

Defects in genetic and developmental processes are thought to contribute susceptibility to
autism and schizophrenia. Presumably, owing to etiological complexity identifying …

Schizophrenia, schizoaffective disorder, and bipolar disorder are common psychiatric
disorders with high heritabilities and variable phenotypes. The Disrupted in Schizophrenia 1 …

The dog has emerged as a premier species for the study of morphology, behavior, and
disease. The recent availability of a high-quality draft sequence lifts the dog system to a new …

This well-organized and clearly written text has a unique focus on methods of identifying the
joint effects of genes and environment on disease patterns. It follows the natural sequence of …

This article reviews evidence that bipolar disorder (BPD) and schizophrenia (SZ) share
familial risk characteristics. The topic is introduced with a brief discussion of various shared …

Large exploratory studies, including candidate-gene–association testing, genomewide
linkage-disequilibrium scans, and array-expression experiments, are becoming increasingly …

We report a comparative genetic characterization of two population isolates with parallel
demographic histories: the Central Valley of Costa Rica (CVCR) and Antioquia (in northwest …

We explore the implications of the false discovery rate (FDR) controlling procedure in
disease gene map**. With the aid of simulations, we show how, under models commonly …

The goal of this study was to identify susceptibility loci shared by schizophrenia (SZ) and
bipolar disorder (BP), or specific to each. To this end, we performed a dense genome scan …