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Single-cell epigenomics and spatiotemporal transcriptomics reveal human cerebellar development
S Zhong, M Wang, L Huang, Y Chen, Y Ge… - Nature …, 2023 - nature.com
Human cerebellar development is orchestrated by molecular regulatory networks to achieve
cytoarchitecture and coordinate motor and cognitive functions. Here, we combined single …
cytoarchitecture and coordinate motor and cognitive functions. Here, we combined single …
Human photoreceptor cells from different macular subregions have distinct transcriptional profiles
The human neural retina is a light sensitive tissue with remarkable spatial and cellular
organization. Compared with the periphery, the central retina contains more densely packed …
organization. Compared with the periphery, the central retina contains more densely packed …
Neurochemical atlas of the rabbit spinal cord
A Veshchitskii, P Shkorbatova… - Brain Structure and …, 2024 - Springer
Complex neurophysiological and morphologic experiments require suitable animal models
for investigation. The rabbit is one of the most successful models for studying spinal cord …
for investigation. The rabbit is one of the most successful models for studying spinal cord …
An allelic series of spontaneous Rorb mutant mice exhibit a gait phenotype, changes in retina morphology and behavior, and gene expression signatures associated …
GC Murray, JA Bubier, OJ Zinder… - G3: Genes …, 2023 - academic.oup.com
The Retinoid-related orphan receptor beta (RORβ) gene encodes a developmental
transcription factor and has 2 predominant isoforms created through alternative first exon …
transcription factor and has 2 predominant isoforms created through alternative first exon …
Decay of skin-specific gene modules in Pangolins
B Pinto, R Valente, F Caramelo, R Ruivo… - Journal of Molecular …, 2023 - Springer
The mammalian skin exhibits a rich spectrum of evolutionary adaptations. The
pilosebaceous unit, composed of the hair shaft, follicle, and the sebaceous gland, is the …
pilosebaceous unit, composed of the hair shaft, follicle, and the sebaceous gland, is the …
Comparative analysis of genomic inbreeding parameters and runs of homozygosity islands in several fancy and meat rabbit breeds
Runs of homozygosity (ROH) are defined as long stretches of DNA homozygous at each
polymorphic position. The proportion of genome covered by ROH and their length are …
polymorphic position. The proportion of genome covered by ROH and their length are …
Genomic profile of Parkinson's disease in Asians
Parkinson's Disease (PD) has witnessed an alarming rise in prevalence, highlighting the
suboptimal nature of early diagnostic and therapeutic strategies. To address this issue …
suboptimal nature of early diagnostic and therapeutic strategies. To address this issue …
Population genomic structures and signatures of selection define the genetic uniqueness of several fancy and meat rabbit breeds
Following the recent domestication process of the European rabbit (Oryctolagus cuniculus),
many different breeds and lines, distinguished primarily by exterior traits such as coat colour …
many different breeds and lines, distinguished primarily by exterior traits such as coat colour …
[LLIBRE][B] Mouse Genetic Approaches to Understand Neurological Phenotypes
GC Murray - 2024 - search.proquest.com
Rare diseases, though individually uncommon, collectively affect approximately 350 million
people worldwide, and there are no effective treatments for most rare diseases. Rare …
people worldwide, and there are no effective treatments for most rare diseases. Rare …
An allelic series of spontaneous mutations in Rorb cause a gait phenotype, retinal abnormalities, and transcriptomic changes relevant to human neurodevelopmental …
GC Murray, J Bubier, OJ Zinder, B Harris, J Clark… - bioRxiv, 2021 - biorxiv.org
ABSTRACT Rorb encodes the Retinoic Acid Receptor-related orphan receptor beta.
Mutations in either of the two transcripts of Rorb cause defects in multiple systems, including …
Mutations in either of the two transcripts of Rorb cause defects in multiple systems, including …