Sphingolipids and phospholipids in insulin resistance and related metabolic disorders

PJ Meikle, SA Summers - Nature Reviews Endocrinology, 2017 - nature.com
Obesity, insulin resistance, type 2 diabetes mellitus and cardiovascular disease form a
metabolic disease continuum that has seen a dramatic increase in prevalence in developed …

[HTML][HTML] Functions of plasmalogen lipids in health and disease

NE Braverman, AB Moser - Biochimica et Biophysica Acta (BBA)-Molecular …, 2012 - Elsevier
Plasmalogens are a unique class of membrane glycerophospholipids containing a fatty
alcohol with a vinyl-ether bond at the sn-1 position, and enriched in polyunsaturated fatty …

Low-input lipidomics reveals lipid metabolism remodelling during early mammalian embryo development

L Zhang, J Zhao, SM Lam, L Chen, Y Gao, W Wang… - Nature Cell …, 2024 - nature.com
Lipids are indispensable for energy storage, membrane structure and cell signalling.
However, dynamic changes in various categories of endogenous lipids in mammalian early …

Plasmalogens: A potential therapeutic target for neurodegenerative and cardiometabolic disease

S Paul, GI Lancaster, PJ Meikle - Progress in lipid research, 2019 - Elsevier
Plasmalogens are a class of membrane glycerophospholipids with unique properties. They
contain a vinyl-ether linked alkyl chain at the sn-1 position of the glycerol backbone and …

Plasmalogen lipids: functional mechanism and their involvement in gastrointestinal cancer

MCF Messias, GC Mecatti, DG Priolli… - Lipids in Health and …, 2018 - Springer
The plasmalogens are a class of glycerophospholipids which contain a vinyl-ether and an
ester bond at the sn-1 and sn-2 positions, respectively, in the glycerol backbone. They …

Plasmalogens the neglected regulatory and scavenging lipid species

S Wallner, G Schmitz - Chemistry and physics of lipids, 2011 - Elsevier
Plasmalogens are a class of phospholipids carrying a vinyl ether bond in sn-1 and an ester
bond in sn-2 position of the glycerol backbone. Although they are widespread in all tissues …

Rapid and comprehensive 'shotgun'lipidome profiling of colorectal cancer cell derived exosomes

TA Lydic, S Townsend, CG Adda, C Collins… - Methods, 2015 - Elsevier
There is an increasing recognition of the role that cancer cell derived exosomes play in
intercellular signaling upon fusion or uptake with a target cell, including immune system …

From peroxisomal disorders to common neurodegenerative diseases–the role of ether phospholipids in the nervous system

F Dorninger, S Forss‐Petter, J Berger - FEBS letters, 2017 - Wiley Online Library
The emerging diverse roles of ether (phospho) lipids in nervous system development and
function in health and disease are currently attracting growing interest. Plasmalogens, a …

[HTML][HTML] Chronic inflammation, neuroglial dysfunction, and plasmalogen deficiency as a new pathobiological hypothesis addressing the overlap between post-COVID …

AM Chaves-Filho, O Braniff, A Angelova, Y Deng… - Brain Research …, 2023 - Elsevier
After five waves of coronavirus disease 2019 (COVID-19) outbreaks, it has been recognized
that a significant portion of the affected individuals developed long-term debilitating …

Lipidomics of Alzheimer's disease: current status

PL Wood - Alzheimer's research & therapy, 2012 - Springer
Alzheimer's disease (AD) is a cognitive disorder with a number of complex
neuropathologies, including, but not limited to, neurofibrillary tangles, neuritic plaques …