Designing biological compartmentalization

AH Chen, PA Silver - Trends in cell biology, 2012 - cell.com
Intracellular organization is a key factor in cell metabolism. Cells have evolved various
organizational systems to solve the challenges of toxic pathway intermediates, competing …

Immunoinformatics: In Silico Approaches and Computational Design of a Multi-epitope, Immunogenic Protein

AA Bahrami, Z Payandeh, S Khalili… - International reviews …, 2019 - Taylor & Francis
Immunoinformatics is a new critical field with several tools and databases that conduct the
eyesight of experimental selection and facilitate analysis of the great amount of immunologic …

Multi-purpose RNA language modelling with motif-aware pretraining and type-guided fine-tuning

N Wang, J Bian, Y Li, X Li, S Mumtaz, L Kong… - Nature Machine …, 2024 - nature.com
Pretrained language models have shown promise in analysing nucleotide sequences, yet a
versatile model excelling across diverse tasks with a single pretrained weight set remains …

Interpretable RNA foundation model from unannotated data for highly accurate RNA structure and function predictions

J Chen, Z Hu, S Sun, Q Tan, Y Wang, Q Yu… - arxiv preprint arxiv …, 2022 - arxiv.org
Non-coding RNA structure and function are essential to understanding various biological
processes, such as cell signaling, gene expression, and post-transcriptional regulations …

Beacon: Benchmark for comprehensive rna tasks and language models

Y Ren, Z Chen, L Qiao, H **g, Y Cai… - Advances in …, 2025 - proceedings.neurips.cc
RNA plays a pivotal role in translating genetic instructions into functional outcomes,
underscoring its importance in biological processes and disease mechanisms. Despite the …

UFold: fast and accurate RNA secondary structure prediction with deep learning

L Fu, Y Cao, J Wu, Q Peng, Q Nie… - Nucleic acids research, 2022 - academic.oup.com
For many RNA molecules, the secondary structure is essential for the correct function of the
RNA. Predicting RNA secondary structure from nucleotide sequences is a long-standing …

ViennaRNA Package 2.0

R Lorenz, SH Bernhart… - Algorithms for molecular …, 2011 - Springer
Background Secondary structure forms an important intermediate level of description of
nucleic acids that encapsulates the dominating part of the folding energy, is often well …

NNDB: the nearest neighbor parameter database for predicting stability of nucleic acid secondary structure

DH Turner, DH Mathews - Nucleic acids research, 2010 - academic.oup.com
ABSTRACT The Nearest Neighbor Database (NNDB, http://rna. urmc. rochester. edu/NNDB)
is a web-based resource for disseminating parameter sets for predicting nucleic acid …

Kinefold web server for RNA/DNA folding path and structure prediction including pseudoknots and knots

A Xayaphoummine, T Bucher… - Nucleic acids research, 2005 - academic.oup.com
The Kinefold web server provides a web interface for stochastic folding simulations of
nucleic acids on second to minute molecular time scales. Renaturation or co-transcriptional …

Paradigms for computational nucleic acid design

RM Dirks, M Lin, E Winfree, NA Pierce - Nucleic acids research, 2004 - academic.oup.com
The design of DNA and RNA sequences is critical for many endeavors, from DNA
nanotechnology, to PCR‐based applications, to DNA hybridization arrays. Results in the …