High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents

P Kanjanasirirat, A Suksatu, S Manopwisedjaroen… - Scientific reports, 2020 - nature.com
Since December 2019, the emergence of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) has caused severe pneumonia, a disease named COVID-19, that became …

Nephroprotective activity of medicinal plants: A review on in silico-, in vitro-, and in vivo-based studies

D Sujana, NM Saptarini, SA Sumiwi… - Journal of Applied …, 2021 - japsonline.com
Acute kidney injury (AKI) is a severe problem for healthcare professionals due to its high
mortality rate. The major causes of AKI are ischemia, hypoxia, and drug-induced …

Traditional wisdom in modern medicine: unveiling the anticancer efficacy of Northeastern Indian spices

P Borah, A Baral, AK Paul, U Ray, R Bharalee… - Journal of Herbal …, 2024 - Elsevier
Introduction Spices, derived from plant products, contain distinct aromatic substances that
enhance the, flavour, taste, and overall quality of food. The rich diversity in flora, fauna, and …

Induction of apoptosis in human colorectal cancer cells by nanovesicles from fingerroot (Boesenbergia rotunda (L.) Mansf.)

S Wongkaewkhiaw, A Wongrakpanich, S Krobthong… - PLoS …, 2022 - journals.plos.org
Colorectal cancer is the leading cause of cancer-related deaths worldwide, warranting the
urgent need for a new treatment option. Plant-derived nanovesicles containing bioactive …

Interaction of panduratin A and derivatives with the SARS-CoV-2 main protease (mpro): a molecular docking study

G Vergoten, C Bailly - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Abstract Panduratin A (Pa-A) is a prenylated cyclohexenyl chalcone isolated from the
rhizomes of the medicinal and culinary plant Boesenbergia rotunda (L.) Mansf., commonly …

Boesenbergia rotunda (L.) Mansf.: A Review of Phytochemistry, Pharmacology, and Pharmacokinetics

NQ Hop, N The Son - Current Organic Chemistry, 2023 - benthamdirect.com
Boesenbergia rotunda (the family Zingiberaceae) is a well-known medicinal plant from
Southeast Asia and China. Its parts, especially the roots, were used as an alternative in …

Evodiamine inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cells via the SRC/ERBB2-mediated MAPK/ERK signaling pathway

J Liu, L He, W Zhang, Y Tang, J Fan, Y He - Journal of translational …, 2024 - Springer
This study aimed to investigate the effect and potential mechanism of evodiamine (EVO) on
proliferation and apoptosis of nasopharyngeal carcinoma (NPC) cells. EVO inhibited …

[HTML][HTML] Novel semi-synthetic Cu (II)–cardamonin complex exerts potent anticancer activity against triple-negative breast and pancreatic cancer cells via inhibition of …

MS Hossan, MKB Break, TD Bradshaw, HM Collins… - Molecules, 2021 - mdpi.com
Cardamonin is a polyphenolic natural product that has been shown to possess cytotoxic
activity against a variety of cancer cell lines. We previously reported the semi-synthesis of a …

The efficacy of natural products for the treatment of nasopharyngeal carcinoma

X Ao, C Luo, M Zhang, L Liu… - Chemical Biology & Drug …, 2024 - Wiley Online Library
Nasopharyngeal carcinoma (NPC) is a malignant tumor originating in the nasopharyngeal
epithelium with a high incidence in southern China and parts of Southeast Asia. The current …

Complete chloroplast genome of Boesenbergia rotunda and a comparative analysis with members of the family Zingiberaceae

YJM Liew, KO Chua, HS Yong, SL Song… - Brazilian Journal of …, 2022 - Springer
Abstract Boesenbergia rotunda (L.) Mansf. is a medically important ginger species of the
family Zingiberaceae but its genomic information on molecular phylogeny and identification …