Background The literature regarding clinical olfaction, olfactory loss, and olfactory
dysfunction has expanded rapidly over the past two decades, with an exponential rise in the …

The capacity of the olfactory epithelium (OE) for lifelong neurogenesis and regeneration
depends on the persistence of neurocompetent stem cells, which self‐renew as well as …

Stromal cells (SCs) establish the compartmentalization of lymphoid tissues critical to the
immune response. However, the full diversity of lymph node (LN) SCs remains undefined …

The presence of active neurogenic niches in adult humans is controversial. We focused
attention to the human olfactory neuroepithelium, an extracranial site supplying input to the …

A detailed understanding of the paths that stem cells traverse to generate mature progeny is
vital for elucidating the mechanisms governing cell fate decisions and tissue homeostasis …

The olfactory neuroepithelium serves as a sensory organ for odors and forms part of the
nasal mucosal barrier. Olfactory sensory neurons are surrounded and supported by …

Disorders causing a loss of the sense of smell remain a therapeutic challenge. Basic
research has, however, greatly expanded our knowledge of the organization and function of …

In 1935, the olfactory route was hypothesized to be a portal for virus entry into the central
nervous system (CNS). This hypothesis was based on experiments in which nasophayngeal …

Adult neurogenesis in the olfactory epithelium is often depicted as a unidirectional pathway
during homeostasis and repair. We challenge the unidirectionality of this model by showing …

The degree to which cKit-expressing progenitors generate cardiomyocytes in the heart is
controversial. Genetic fate-map** studies suggest minimal contribution; however, whether …