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GLUT1-mediated microglial proinflammatory activation contributes to the development of stress-induced spatial learning and memory dysfunction in mice
X Wang, Y Wu, Y Tian, H Hu, Y Zhao, B Xue, Z Sun… - Cell & Bioscience, 2024 - Springer
Background Stress is a recognized risk factor for cognitive decline, which triggers
neuroinflammation involving microglial activation. However, the specific mechanism for …
neuroinflammation involving microglial activation. However, the specific mechanism for …
Folic Acid and Folinic Acid Protect Hearts of Aging Triple-transgenic Alzheimer's Disease mice via IGF1R/PI3K/AKT and SIRT1/AMPK Pathways
DT Ju, RFS Huang, BCK Tsai, YC Su, PL Chiu… - Neurotoxicity …, 2023 - Springer
Patients with Alzheimer's disease have increased risk of develo** heart disease, which
therefore highlights the need for strategies aiming at reducing Alzheimer's disease-related …
therefore highlights the need for strategies aiming at reducing Alzheimer's disease-related …
Enhanced IGF‐IIRα Expression Exacerbates Lipopolysaccharide‐Induced Cardiac Inflammation, Hypertrophy, and Apoptosis Through Calcineurin Activation
Cardiovascular disease is one of the leading causes of death worldwide and has a high
prevalence. Insulin‐like growth factor‐II receptor α (IGF‐IIRα) acts as a stress‐inducible …
prevalence. Insulin‐like growth factor‐II receptor α (IGF‐IIRα) acts as a stress‐inducible …
[HTML][HTML] Inhibition of Glycolysis Alleviates Chronic Unpredictable Mild Stress Induced Neuroinflammation and Depression-like Behavior
B Liu, K Dong, X Chen, H Dong, Y Zhao, X Wang… - Brain Sciences, 2024 - mdpi.com
Background: Growing evidence suggests that glucose metabolism plays a crucial role in
activated immune cells, significantly contributing to the occurrence and development of …
activated immune cells, significantly contributing to the occurrence and development of …
Novel chromium (III)-based compound for inhibition of oxaliplatin-resistant colorectal cancer progression
MC Chen, HS Devi, HF Pien, SFM Wen… - American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Colorectal cancer (CRC) ranks as the third leading cause of cancer-related mortality
worldwide. The current standard of care includes systemic chemotherapy with cytotoxic …
worldwide. The current standard of care includes systemic chemotherapy with cytotoxic …
Cardiac-specific overexpression of insulin-like growth factor II receptor-α interferes with the regulation of calcium homeostasis in the heart under hyperglycemic …
SY Lu, BCK Tsai, D Van Thao, CH Lai… - Molecular Biology …, 2023 - Springer
Background Diabetic cardiomyopathy is a progressive disease caused by inexplicit
mechanisms, and a novel factor, insulin-like growth factor II receptor-α (IGF-IIRα), may …
mechanisms, and a novel factor, insulin-like growth factor II receptor-α (IGF-IIRα), may …
Development and evaluation of a novel chromium III-based compound for potential inhibition of emerging SARS-CoV-2 variants
YJ Lin, N Sundhar, HS Devi, HF Pien, SFM Wen… - Heliyon, 2023 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused 403 million
cases of coronavirus disease (COVID-19) and resulted in more than 5.7 million deaths …
cases of coronavirus disease (COVID-19) and resulted in more than 5.7 million deaths …