Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy

G Sloan, D Selvarajah, S Tesfaye - Nature Reviews Endocrinology, 2021 - nature.com
Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

Epidemiology of peripheral neuropathy and lower extremity disease in diabetes

CW Hicks, E Selvin - Current diabetes reports, 2019 - Springer
Abstract Purpose of Review Diabetic peripheral neuropathy eventually affects nearly 50% of
adults with diabetes during their lifetime and is associated with substantial morbidity …

Diabetic peripheral neuropathy: advances in diagnosis and strategies for screening and early intervention

D Selvarajah, D Kar, K Khunti, MJ Davies… - The lancet Diabetes & …, 2019 - thelancet.com
Diabetic peripheral neuropathy (DPN) is a common complication of both type 1 and 2
diabetes. It is a leading cause of lower-limb amputation and disabling neuropathic pain …

Diabetic neuropathy: a position statement by the American Diabetes Association

R Pop-Busui, AJM Boulton, EL Feldman, V Bril… - Diabetes …, 2016 - pmc.ncbi.nlm.nih.gov
Diabetic neuropathies are the most prevalent chronic complications of diabetes. This
heterogeneous group of conditions affects different parts of the nervous system and presents …

Effect of high-frequency (10-kHz) spinal cord stimulation in patients with painful diabetic neuropathy: a randomized clinical trial

EA Petersen, TG Stauss, JA Scowcroft… - JAMA …, 2021 - jamanetwork.com
Importance Many patients with diabetic peripheral neuropathy experience chronic pain and
inadequate relief despite best available medical treatments. Objective To determine whether …

Diabetic neuropathy: mechanisms, emerging treatments, and subtypes

JW Albers, R Pop-Busui - Current neurology and neuroscience reports, 2014 - Springer
Diabetic neuropathies (DNs) differ in clinical course, distribution, fiber involvement (type and
size), and pathophysiology, the most typical type being a length-dependent distal symmetric …

Understanding diabetic neuropathy: focus on oxidative stress

L Pang, X Lian, H Liu, Y Zhang, Q Li… - Oxidative Medicine …, 2020 - Wiley Online Library
Diabetic neuropathy is one of the clinical syndromes characterized by pain and substantial
morbidity primarily due to a lesion of the somatosensory nervous system. The burden of …

New perspective in diabetic neuropathy: from the periphery to the brain, a call for early detection, and precision medicine

H Yang, G Sloan, Y Ye, S Wang, B Duan… - Frontiers in …, 2020 - frontiersin.org
Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes
mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg …

Emerging biomarkers, tools, and treatments for diabetic polyneuropathy

GJ Bönhof, C Herder, A Strom, N Papanas… - Endocrine …, 2019 - academic.oup.com
Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers,
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …

Current concepts in the management of diabetic polyneuropathy

D Ziegler, N Papanas, O Schnell… - Journal of Diabetes …, 2021 - Wiley Online Library
Diabetic sensorimotor polyneuropathy (DSPN) is encountered in approximately one‐third of
people with diabetes. This, in turn, might markedly impoverish their quality of life, mainly …