The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …

Nitric oxide (NO) is one of the 10 smallest molecules found in nature. It is a simple gaseous
free radical whose predominant functions is that of a messenger through cGMP. In …

Through this work, we have elucidated the mechanism of hydroxyl radicals (OH•) generation
and its life time measurements in biosolution. We observed that plasma-initiated ultraviolet …

The identification of thrombospondin-1 as an angiogenesis inhibitor in 1990 prompted
interest in its role in cancer biology and potential as a therapeutic target. Decreased …

Nitric oxide (NO) is a key player in both the development and suppression of tumourigenesis
depending on the source and concentration of NO. In this review, we discuss the …

Nitric oxide (NO) from endothelial NO synthase importantly contributes to vascular
homeostasis. Reduced NO production or increased scavenging during disease conditions …

Cartilage oligomeric matrix protein (COMP) is a large pentameric glycoprotein that interacts
with multiple extracellular matrix proteins in cartilage and other tissues. While, COMP is …

Thrombospondins TSP-1 and TSP-2 are potent endogenous inhibitors of angiogenesis.
They inhibit angiogenesis through direct effects on endothelial cell migration, proliferation …

Nitric oxide (NO) and nitric oxide synthases are ubiquitous in malignant tumours and are
known to exert both pro-and anti-tumour effects. We summarize our current understanding of …

The term matricellular proteins describes a family of structurally unrelated extracellular
macromolecules that, unlike structural matrix proteins, do not play a primary role in tissue …