Aurora kinases are serine/threonine kinases essential for the onset and progression of
mitosis. Aurora members share a similar protein structure and kinase activity, but exhibit …

Recent studies of N-terminal acetylation have identified new N-terminal acetyltransferases
(NATs) and expanded the known functions of these enzymes beyond their roles as ribosome …

Reversible lysine acetylation is an important post-translational modification (PTM). This
process in cells is typically carried out enzymatically by lysine acetyltransferases and …

Aurora A kinase is a master mitotic regulator whose functions are controlled by several
regulatory interactions and post-translational modifications. It is frequently dysregulated in …

NAA10 is the catalytic subunit of the N-terminal acetyltransferase complex, NatA, which is
responsible for N-terminal acetylation of nearly half the human proteome. Since 2011, at …

Background Diabetes-related limb ischemia is a challenge for lower extremity amputation.
Aurora Kinase A (AURKA) is an essential serine/threonine kinase for mitosis, while its role in …

N-terminal acetylation is a highly abundant protein modification in eukaryotic cells. This
modification is catalysed by N-terminal acetyltransferases acting co-or post-translationally …

Introduction We aimed to investigate the expression and prognostic role of NAA10 in clear
cell renal cell carcinoma (ccRCC). Material and methods We performed a gene expression …

Simple Summary Mono-ADP-ribosylating PARP enzymes are involved in the regulation of
several cellular pathways, including cell cycle. The mono-ADP-ribosyltransferase PARP10 is …

N-α-acetyltransferase 10 (NAA10) is an acetyltransferase that acetylates both N-terminal
amino acid and internal lysine residues of proteins. NAA10 is a crucial player to regulate cell …