Role of endothelial dysfunction in cardiovascular diseases: the link between inflammation and hydrogen sulfide

HJ Sun, ZY Wu, XW Nie, JS Bian - Frontiers in pharmacology, 2020 - frontiersin.org
Endothelial cells are important constituents of blood vessels that play critical roles in
cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos, EH Ohlstein - Pharmacological reviews, 2017 - Elsevier
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

JL Wallace, R Wang - Nature reviews Drug discovery, 2015 - nature.com
Hydrogen sulfide (H2S) has become recognized as an important signalling molecule
throughout the body, contributing to many physiological and pathological processes. In …

Vascular smooth muscle cells in intimal hyperplasia, an update

S Déglise, C Bechelli, F Allagnat - Frontiers in physiology, 2023 - frontiersin.org
Arterial occlusive disease is the leading cause of death in Western countries. Core
contemporary therapies for this disease include angioplasties, stents, endarterectomies and …

The role of perivascular adipose tissue in obesity‐induced vascular dysfunction

N **a, H Li - British journal of pharmacology, 2017 - Wiley Online Library
Under physiological conditions, perivascular adipose tissue (PVAT) attenuates agonist‐
induced vasoconstriction by releasing vasoactive molecules including hydrogen peroxide …

Vascular biology of hydrogen sulfide

NL Kanagy, C Szabo… - American Journal of …, 2017 - journals.physiology.org
Hydrogen sulfide (H2S) is a ubiquitous signaling molecule with important functions in many
mammalian organs and systems. Observations in the 1990s ascribed physiological actions …

[HTML][HTML] Hydrogen sulfide and vascular regulation–An update

B Lv, S Chen, C Tang, H **, J Du, Y Huang - Journal of advanced research, 2021 - Elsevier
Abstract Background Hydrogen sulfide (H 2 S) is considered to be the third gasotransmitter
after carbon monoxide (CO) and nitric oxide (NO). It plays an important role in the regulation …

Hydrogen sulfide in pharmacotherapy, beyond the hydrogen sulfide-donors

E Zaorska, L Tomasova, D Koszelewski, R Ostaszewski… - Biomolecules, 2020 - mdpi.com
Hydrogen sulfide (H2S) is one of the important biological mediators involved in
physiological and pathological processes in mammals. Recently developed H2S donors …

Regulation and role of endogenously produced hydrogen sulfide in angiogenesis

A Katsouda, SI Bibli, A Pyriochou, C Szabo… - Pharmacological …, 2016 - Elsevier
Recent studies have implicated endogenously produced H 2 S in the angiogenic process.
On one hand, pharmacological inhibition and silencing of the enzymes involved in H 2 S …