Isothermal Titration Calorimetry (ITC) elucidates the thermodynamic profile (ΔH, ΔS, ΔG, Ka,
and stoichiometry) of binding and dissociation reactions in solution. While ITC has primarily …

Introduction Drug treatment is one of the main ways of co** with disease today. For the
disadvantages of drug management, thermosensitive hydrogel is used as a …

Mixing of oppositely charged polyelectrolytes can result in phase separation into a polymer-
poor supernatant and a polymer-rich polyelectrolyte complex (PEC). We present a new …

Hypothesis Hydrogels of N-isopropylacrylamide and methacrylic acid (P (NIPAm-co-MAA))
display pH sensitivity and complex positively charged molecules through carboxylate …

Electrochemical responses of glucose oxidase loaded (via electrostatic immobilization) into
a surface-attached pH-and temperature-sensitive copolymer microgel were examined. The …

A chief objective of gene transportation studies is to manipulate clinically accepted carriers
that can be utilized to combat incurable diseases. Despite various strategies, efficiency and …

This study highlights the use of chargeable stimuli-responsive microgels for modification of
rather hydrophobic model surfaces and reveals the optimal conditions, which are to be …

Using a thermodynamic theory, we present a systematic study of the behavior of microgels of
N-isopropylacrylamide (NIPAm) and methacrylic acid (MAA) copolymers as a function of the …

This study explores the impact of network functionalization and chemical composition on the
pH-responsive behavior of polymer nanogels and their adsorption of proteins. Using a …

In vitro models are valuable tools for applications including understanding cellular
mechanisms and drug screening. Hydrogel biomaterials facilitate in vitro models by …