Integration of lipidomics and metabolomics for in-depth understanding of cellular mechanism and disease progression
Mass spectrometry (MS)-based omics technologies are now widely used to profile small
molecules in multiple matrices to confer comprehensive snapshots of cellular metabolic …
molecules in multiple matrices to confer comprehensive snapshots of cellular metabolic …
[HTML][HTML] MicroRNAs in the pathogenesis of nonalcoholic fatty liver disease
Z Fang, G Dou, L Wang - International journal of biological …, 2021 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD), or, more accurately, metabolic associated fatty
liver disease, accounts for a large proportion of chronic liver disorders worldwide and is …
liver disease, accounts for a large proportion of chronic liver disorders worldwide and is …
A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation …
SA Harrison, V Ratziu, J Boursier… - The lancet …, 2020 - thelancet.com
Background Non-invasive tests that can identify patients with non-alcoholic steatohepatitis
(NASH) at higher risk of disease progression are lacking. We report the development and …
(NASH) at higher risk of disease progression are lacking. We report the development and …
[HTML][HTML] The role of lipid metabolism in osteoporosis: Clinical implication and cellular mechanism
J Zhang, W Hu, Z Zou, Y Li, F Kang, J Li, S Dong - Genes & Diseases, 2024 - Elsevier
In recent years, researchers have become focused on the relationship between lipids and
bone metabolism balance. Moreover, many diseases related to lipid metabolism disorders …
bone metabolism balance. Moreover, many diseases related to lipid metabolism disorders …
miR‐21‐5p promotes NASH‐related hepatocarcinogenesis
Abstract Background and Aims The mechanisms governing the progression of non‐
alcoholic fatty liver disease (NAFLD) towards steatohepatitis (NASH) and hepatocellular …
alcoholic fatty liver disease (NAFLD) towards steatohepatitis (NASH) and hepatocellular …
Gut commensal Kineothrix alysoides mitigates liver dysfunction by restoring lipid metabolism and gut microbial balance
KJ Choi, MY Yoon, JE Kim, SS Yoon - Scientific Reports, 2023 - nature.com
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as Non-
Alcoholic Fatty Liver Disease, is a widespread liver condition characterized by excessive fat …
Alcoholic Fatty Liver Disease, is a widespread liver condition characterized by excessive fat …
Gluconeogenesis flux in metabolic disease
A Shah, FE Wondisford - Annual Review of Nutrition, 2023 - annualreviews.org
Gluconeogenesis is a critical biosynthetic process that helps maintain whole-body glucose
homeostasis and becomes altered in certain medical diseases. We review gluconeogenic …
homeostasis and becomes altered in certain medical diseases. We review gluconeogenic …
DSS-induced colitis is associated with adipose tissue dysfunction and disrupted hepatic lipid metabolism leading to hepatosteatosis and dyslipidemia in mice
J Kwon, C Lee, S Heo, B Kim, CK Hyun - Scientific reports, 2021 - nature.com
Considering high prevalence of non-alcoholic fatty liver diseases (NAFLD) in patients with
inflammatory bowel disease (IBD), this study aimed to elucidate molecular mechanisms for …
inflammatory bowel disease (IBD), this study aimed to elucidate molecular mechanisms for …
[HTML][HTML] Physiology, glucose
PJ Hantzidiamantis, AO Awosika, SL Lappin - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
Glucose is a 6-carbon structure with the chemical formula C 6 H 12 O 6. Carbohydrates are
ubiquitous energy sources for every organism worldwide and are essential to fuel aerobic …
ubiquitous energy sources for every organism worldwide and are essential to fuel aerobic …
Liver organoid as a 3D in vitro model for drug validation and toxicity assessment
A Brooks, X Liang, Y Zhang, CX Zhao… - Pharmacological …, 2021 - Elsevier
The past decade has seen many advancements in the development of three-dimensional
(3D) in vitro models in pharmaceutical sciences and industry. Specifically, organoids present …
(3D) in vitro models in pharmaceutical sciences and industry. Specifically, organoids present …