Free radicals, reactive oxygen species, oxidative stress and its classification

VI Lushchak - Chemico-biological interactions, 2014 - Elsevier
Reactive oxygen species (ROS) initially considered as only damaging agents in living
organisms further were found to play positive roles also. This paper describes ROS …

Placental origins of chronic disease

GJ Burton, AL Fowden… - Physiological …, 2016 - journals.physiology.org
Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …

The programming power of the placenta

AN Sferruzzi-Perri, EJ Camm - Frontiers in physiology, 2016 - frontiersin.org
Size at birth is a critical determinant of life expectancy, and is dependent primarily on the
placental supply of nutrients. However, the placenta is not just a passive organ for the …

Resveratrol supplementation of high‐fat diet‐fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring

T Zou, D Chen, Q Yang, B Wang, MJ Zhu… - The Journal of …, 2017 - Wiley Online Library
Key points Maternal high‐fat diet impairs brown adipocyte function and correlates with
obesity in offspring. Maternal resveratrol administration recovers metabolic activity of …

Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex‐dependent manner

KLM Smith, A Swiderska, MC Lock… - Journal of Pineal …, 2022 - Wiley Online Library
Insufficient oxygen supply (hypoxia) during fetal development leads to cardiac remodeling
and a predisposition to cardiovascular disease in later life. Previous work has shown …

Hypoxia: from placental development to fetal programming

L Fajersztajn, MM Veras - Birth defects research, 2017 - Wiley Online Library
Hypoxia may influence normal and different pathological processes. Low oxygenation
activates a variety of responses, many of them regulated by hypoxia‐inducible factor 1 …

[HTML][HTML] Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke

CK Carberry, LE Koval, A Payton, H Hartwell… - Environment …, 2022 - Elsevier
Introduction Wildfires are a threat to public health world-wide that are growing in intensity
and prevalence. The biological mechanisms that elicit wildfire-associated toxicity remain …

Intrauterine growth restriction: impact on cardiovascular development and function throughout infancy

E Cohen, FY Wong, RSC Horne, SR Yiallourou - Pediatric research, 2016 - nature.com
Intrauterine growth restriction (IUGR) refers to the situation where a fetus does not grow
according to its genetic growth potential. One of the main causes of IUGR is uteroplacental …

Resveratrol partially prevents oxidative stress and metabolic dysfunction in pregnant rats fed a low protein diet and their offspring

CC Vega, LA Reyes‐Castro… - The Journal of …, 2016 - Wiley Online Library
Key points Maternal protein restriction during pregnancy increases both maternal and
offspring oxidative stress and leads to metabolic dysfunction. Maternal low protein diet …

Antioxidant paradox in male infertility:'A blind eye'on inflammation

S Dutta, P Sengupta, S Roychoudhury, S Chakravarthi… - Antioxidants, 2022 - mdpi.com
The pathophysiology of male infertility involves various interlinked endogenous pathways.
About 50% of the cases of infertility in men are idiopathic, and oxidative stress (OS) …