Glycosylation is the most abundant and diverse form of post-translational modification of
proteins that is common to all eukaryotic cells. Enzymatic glycosylation of proteins involves a …

The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

The six mammalian glycosaminoglycans (GAGs), chondroitin sulfate, dermatan sulfate,
heparin, heparan sulfate, hyaluronan, and keratan sulfate, are linear polysaccharides …

Glycosaminoglycans (GAGs) are complex polysaccharides exhibiting a vast structural
diversity and fulfilling various functions mediated by thousands of interactions in the …

The structural diversity of glycans on cells—the glycome—is vast and complex to decipher.
Glycan arrays display oligosaccharides and are used to report glycan hapten binding …

Cancer mortality is exacerbated by late-stage diagnosis. Liquid biopsies based on genomic
biomarkers can noninvasively diagnose cancers. However, validation studies have …

Mucins are a large family of heavily O-glycosylated proteins that cover all mucosal surfaces
and constitute the major macromolecules in most body fluids. Mucins are primarily defined …

Two major glycosaminoglycan types, heparan sulfate (HS) and chondroitin sulfate (CS),
control many aspects of development and physiology in a type-specific manner. HS and CS …

Heparan Sulfate Proteoglycans (HSPGs) are important cell surface and Extracellular Matrix
(ECM) maestros involved in the orchestration of multiple cellular events in physiology and …

Leukocyte recruitment from the vasculature into tissues is a crucial component of the
immune system but is also key to inflammatory disease. Chemokines are central to this …