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Microfluidics for drug development: from synthesis to evaluation
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …
delivery, and drug evaluation. Compared with conventional drug development procedures …
High-throughput methods in the discovery and study of biomaterials and materiobiology
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …
pivotal role in the development of novel implants, biomedical devices, and tissue …
[BOG][B] Culture of animal cells: a manual of basic technique and specialized applications
RI Freshney - 2015 - books.google.com
Since the publication of the sixth edition of this benchmark text, numerous advances in the
field have been made–particularly in stem cells, 3D culture, scale-up, STR profiling, and …
field have been made–particularly in stem cells, 3D culture, scale-up, STR profiling, and …
Laser assisted bioprinting of engineered tissue with high cell density and microscale organization
B Guillotin, A Souquet, S Catros, M Duocastella… - Biomaterials, 2010 - Elsevier
Over this decade, cell printing strategy has emerged as one of the promising approaches to
organize cells in two and three dimensional engineered tissues. High resolution and high …
organize cells in two and three dimensional engineered tissues. High resolution and high …
Designing materials to direct stem-cell fate
Proper tissue function and regeneration rely on robust spatial and temporal control of
biophysical and biochemical microenvironmental cues through mechanisms that remain …
biophysical and biochemical microenvironmental cues through mechanisms that remain …
Adaptation of high-throughput screening in drug discovery—toxicological screening tests
P Szymański, M Markowicz… - International journal of …, 2011 - mdpi.com
High-throughput screening (HTS) is one of the newest techniques used in drug design and
may be applied in biological and chemical sciences. This method, due to utilization of …
may be applied in biological and chemical sciences. This method, due to utilization of …
Microfabricated biomaterials for engineering 3D tissues
Mimicking natural tissue structure is crucial for engineered tissues with intended
applications ranging from regenerative medicine to biorobotics. Native tissues are highly …
applications ranging from regenerative medicine to biorobotics. Native tissues are highly …
Spatially and temporally controlled hydrogels for tissue engineering
Recent years have seen tremendous advances in the field of hydrogel-based biomaterials.
One of the most prominent revolutions in this field has been the integration of elements or …
One of the most prominent revolutions in this field has been the integration of elements or …
Recent advances in multicellular tumor spheroid generation for drug screening
KH Lee, TH Kim - Biosensors, 2021 - mdpi.com
Multicellular tumor spheroids (MCTs) have been employed in biomedical fields owing to
their advantage in designing a three-dimensional (3D) solid tumor model. For controlling …
their advantage in designing a three-dimensional (3D) solid tumor model. For controlling …
Beyond annexin V: fluorescence response of cellular membranes to apoptosis
AP Demchenko - Cytotechnology, 2013 - Springer
Dramatic changes in the structure of cell membranes on apoptosis allow easy, sensitive and
non-destructive analysis of this process with the application of fluorescence methods. The …
non-destructive analysis of this process with the application of fluorescence methods. The …