Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine

MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Advances and limitations of drug delivery systems formulated as eye drops

C Jumelle, S Gholizadeh, N Annabi, R Dana - Journal of Controlled …, 2020 - Elsevier
Topical instillation of eye drops remains the most common and easiest route of ocular drug
administration, representing the treatment of choice for many ocular diseases. Nevertheless …

Lipid nanoparticles as a promising drug delivery carrier for topical ocular therapy—an overview on recent advances

S Jacob, AB Nair, J Shah, S Gupta, SHS Boddu… - Pharmaceutics, 2022 - mdpi.com
Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …

Lab‐on‐a‐Contact Lens: Recent Advances and Future Opportunities in Diagnostics and Therapeutics

Y Zhu, S Li, J Li, N Falcone, Q Cui, S Shah… - Advanced …, 2022 - Wiley Online Library
The eye is one of the most complex organs in the human body, containing rich and critical
physiological information (eg, intraocular pressure, corneal temperature, and pH) as well as …

Drug delivery challenges and current progress in nanocarrier-based ocular therapeutic system

MH Akhter, I Ahmad, MY Alshahrani, AI Al-Harbi… - Gels, 2022 - mdpi.com
Drug instillation via a topical route is preferred since it is desirable and convenient due to the
noninvasive and easy drug access to different segments of the eye for the treatment of …

Emerging nano-formulations and nanomedicines applications for ocular drug delivery

D Khiev, ZA Mohamed, R Vichare, R Paulson, S Bhatia… - Nanomaterials, 2021 - mdpi.com
Ocular diseases can deteriorate vision to the point of blindness and thus can have a major
impact on the daily life of an individual. Conventional therapies are unable to provide …

Sustained delivery system for stem cell-derived exosomes

AK Riau, HS Ong, GHF Yam, JS Mehta - Frontiers in pharmacology, 2019 - frontiersin.org
Recent literature has ascribed that the paracrine action of stem cells is mediated by
exosomes. Exosomes are nano-sized extracellular vesicles (30 to 100 nm) of endocytic …

[HTML][HTML] A review on recent drug delivery systems for posterior segment of eye

K Nayak, M Misra - Biomedicine & pharmacotherapy, 2018 - Elsevier
Eye is the unique sense organ with complex and sophisticated anatomy and physiology.
Being most instrumental for vision, it is secured by varied protective barriers; ranging from …

Nanomaterial-based ophthalmic drug delivery

G **e, S Lin, F Wu, J Liu - Advanced drug delivery reviews, 2023 - Elsevier
The low bioavailability and side effects of conventional drugs for eye disease necessitate the
development of efficient drug delivery systems. Accompanying the developments of …