Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …

Phytocannabinoids are bioactive natural products found in some flowering plants, liverworts,
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …

The year 2017 marks the twentieth anniversary of terpenoid cyclase structural biology: a trio
of terpenoid cyclase structures reported together in 1997 were the first to set the foundation …

The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …

All plants synthesize a diverse array of terpenoid metabolites. Some are common to all, but
many are synthesized only in specific taxa and presumably evolved as adaptations to …

Terpenoids comprise tens of thousands of small molecule natural products that are widely
distributed across all domains of life. Plants produce by far the largest array of terpenoids …

Natural product libraries contain specialized metabolites derived from plants, animals, and
microorganisms that play a pivotal role in drug discovery due to their immense structural …

Covering: 2013 to 2021 As the characteristic metabolites of Euphorbia plants, Euphorbia
diterpenoids have always been a hot topic in related science communities due to their …

In plant terpene biosynthesis, oxidation of the hydrocarbon backbone produced by terpene
synthases is typically carried out by cytochrome P450 oxygenases (CYPs). The …

Covering: 2000 to 2020 Triptolide is a bioactive diterpene triepoxide isolated from
Tripterygium wilfordii Hook F, a traditional Chinese medicinal plant whose extracts have …