Retinal Connectomics: A Review

CL Sigulinsky, RL Pfeiffer… - Annual Review of Vision …, 2024 - annualreviews.org
The retina is an ideal model for understanding the fundamental rules for how neural
networks are constructed. The compact neural networks of the retina perform all of the initial …

Homeostatic plasticity in the retina

MJ Fitzpatrick, D Kerschensteiner - Progress in Retinal and Eye Research, 2023 - Elsevier
Vision begins in the retina, whose intricate neural circuits extract salient features of the
environment from the light entering our eyes. Neurodegenerative diseases of the retina (eg …

Troubling collaboration: Matters of care for visualization design study

D Akbaba, D Lange, M Correll, A Lex… - Proceedings of the 2023 …, 2023 - dl.acm.org
A common research process in visualization is for visualization researchers to collaborate
with domain experts to solve particular applied data problems. While there is existing …

Distributed feature representations of natural stimuli across parallel retinal pathways

JC Hsiang, N Shen, F Soto… - Nature communications, 2024 - nature.com
How sensory systems extract salient features from natural environments and organize them
across neural pathways is unclear. Combining single-cell and population two-photon …

Hierarchical retinal computations rely on hybrid chemical-electrical signaling

L Hanson, P Ravi-Chander, D Berson, GB Awatramani - Cell Reports, 2023 - cell.com
Bipolar cells (BCs) are integral to the retinal circuits that extract diverse features from the
visual environment. They bridge photoreceptors to ganglion cells, the source of retinal …

[HTML][HTML] A pathoconnectome of early neurodegeneration: Network changes in retinal degeneration

RL Pfeiffer, JR Anderson, J Dahal, JC Garcia… - Experimental eye …, 2020 - Elsevier
Connectomics has demonstrated that synaptic networks and their topologies are precise
and directly correlate with physiology and behavior. The next extension of connectomics is …

Electrical synaptic transmission requires a postsynaptic scaffolding protein

AM Lasseigne, FA Echeverry, S Ijaz, JC Michel… - Elife, 2021 - elifesciences.org
Electrical synaptic transmission relies on neuronal gap junctions containing channels
constructed by Connexins. While at chemical synapses neurotransmitter-gated ion channels …

Analysis of rod/cone gap junctions from the reconstruction of mouse photoreceptor terminals

M Ishibashi, J Keung, CW Morgans, SA Aicher… - Elife, 2022 - elifesciences.org
Electrical coupling, mediated by gap junctions, contributes to signal averaging,
synchronization, and noise reduction in neuronal circuits. In addition, gap junctions may also …

Functionally distinct circuits are linked by heterocellular electrical synapses in the thalamic reticular nucleus

MJ Vaughn, Z Laswick, H Wang, JS Haas - eneuro, 2024 - eneuro.org
The thalamic reticular nucleus (TRN) inhibits sensory thalamocortical relay neurons and is a
key regulator of sensory attention as well as sleep and wake states. Recent developments …

Spatiotemporal properties of glutamate input support direction selectivity in the dendrites of retinal starburst amacrine cells

P Srivastava, G de Rosenroll, A Matsumoto, T Michaels… - Elife, 2022 - elifesciences.org
The asymmetric summation of kinetically distinct glutamate inputs across the dendrites of
retinal 'starburst'amacrine cells is one of the several mechanisms that have been proposed …