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[HTML][HTML] Early state research on antifungal natural products
Nosocomial infections caused by fungi have increased greatly in recent years, mainly due to
the rising number of immunocompromised patients. However, the available antifungal …
the rising number of immunocompromised patients. However, the available antifungal …
Insights into the structure and drug design of benzimidazole derivatives targeting the epidermal growth factor receptor (EGFR)
Tyrosine kinase overexpression could result in an unfavourable consequence of cancer
progression in the body. A number of kinase inhibitor drugs targeting various cancer‐related …
progression in the body. A number of kinase inhibitor drugs targeting various cancer‐related …
Synthesis and investigation of novel benzimidazole derivatives as antifungal agents
The rise and emergence of resistance to antifungal drugs by diverse pathogenic fungal
strains have resulted in an increase in demand for new antifungal agents. Various …
strains have resulted in an increase in demand for new antifungal agents. Various …
Phytochemical analysis, antioxidant, and antimicrobial activities of Jordanian Pomegranate peels
Pomegranate (Punica granatum) peels have shown numerous health benefits such as
antioxidant, anti-inflammatory, and antimicrobial activities. These health activities are owed …
antioxidant, anti-inflammatory, and antimicrobial activities. These health activities are owed …
Antifungal drug testing by combining minimal inhibitory concentration testing with target identification by gas chromatography–mass spectrometry
Fungal infections and their increasing resistance to antibiotics are an emerging threat to
public health. Novel antifungal drugs, as well technologies that can help us bolster the …
public health. Novel antifungal drugs, as well technologies that can help us bolster the …
Antifungal defense of probiotic Lactobacillus rhamnosus GG is mediated by blocking adhesion and nutrient depletion
D Mailänder-Sánchez, C Braunsdorf, C Grumaz… - PloS one, 2017 - journals.plos.org
Candida albicans is an inhabitant of mucosal surfaces in healthy individuals but also the
most common cause of fungal nosocomial blood stream infections, associated with high …
most common cause of fungal nosocomial blood stream infections, associated with high …
An antifungal benzimidazole derivative inhibits ergosterol biosynthesis and reveals novel sterols
P Keller, C Müller, I Engelhardt, E Hiller… - Antimicrobial agents …, 2015 - journals.asm.org
Fungal infections are a leading cause of morbidity and death for hospitalized patients,
mainly because they remain difficult to diagnose and to treat. Diseases range from …
mainly because they remain difficult to diagnose and to treat. Diseases range from …
Synthesis, biological evaluation and mechanistic studies of 4-(1, 3-thiazol-2-yl) morpholine-benzimidazole hybrids as a new structural class of antimicrobials
In spite of several attempts to develop newer pharmacophores as potential antimicrobial
agents, the benzimidazole scaffold is still considered as one of the most sought after …
agents, the benzimidazole scaffold is still considered as one of the most sought after …
Design and synthesis of 1‑sec/tert‑butyl-2-chloro/nitrophenylbenzimidazole derivatives: Molecular docking and in vitro evaluation against MDA-MB-231 and MCF-7 …
Breast cancer is the most common type of cancer among women and the increasing cases
of drug resistance pose a great challenge in the development of new anticancer drugs …
of drug resistance pose a great challenge in the development of new anticancer drugs …
A convenient cellular assay for the identification of the molecular target of ergosterol biosynthesis inhibitors and quantification of their effects on total ergosterol …
C Müller, V Staudacher, J Krauss, M Giera, F Bracher - Steroids, 2013 - Elsevier
Increasing resistance of clinically relevant fungi is causing major problems in anti-mycotic
therapy. Particularly for immunosuppressed patients fungal infections are of concern and …
therapy. Particularly for immunosuppressed patients fungal infections are of concern and …