Modeling and prediction of flow-induced hemolysis: a review

MM Faghih, MK Sharp - Biomechanics and modeling in mechanobiology, 2019 - Springer
Despite decades of research related to hemolysis, the accuracy of prediction algorithms for
complex flows leaves much to be desired. Fundamental questions remain about how …

The disconnect between extracorporeal circulation and the microcirculation: A review

K Govender, VP Jani, P Cabrales - ASAIO journal, 2022 - journals.lww.com
Extracorporeal circulation (ECC) procedures, such as cardiopulmonary bypass (CPB) and
extracorporeal membrane oxygenation (ECMO), take over the function of one or more …

Fluid dynamics in the HeartMate 3: influence of the artificial pulse feature and residual cardiac pulsation

L Wiegmann, B Thamsen, D De Zélicourt… - Artificial …, 2019 - Wiley Online Library
Ventricular assist devices (VADs), among which the HeartMate 3 (HM3) is the latest clinically
approved representative, are often the therapy of choice for patients with end‐stage heart …

[HTML][HTML] Computational fluid dynamics analysis and experimental hemolytic performance of three clinical centrifugal blood pumps: Revolution, Rotaflow and …

D Han, JL Leibowitz, L Han, S Wang, G He… - Medicine in novel …, 2022 - Elsevier
Centrifugal blood pumps have become popular for adult extracorporeal membrane
oxygenation (ECMO) due to their superior blood handling and reduced thrombosis risk …

Numerical assessment of hemodynamic perspectives of a left ventricular assist device and subsequent proposal for improvisation

PK Ray, AK Das, PK Das - Computers in Biology and Medicine, 2022 - Elsevier
Due to the unavailability of donors, the use of left ventricular assist devices has emerged to
be a reliable line of alternative treatment for heart failure. However, ventricular assist devices …

Models of shear-induced platelet activation and numerical implementation with computational fluid dynamics approaches

D Han, J Zhang, BP Griffith… - Journal of …, 2022 - asmedigitalcollection.asme.org
Shear-induced platelet activation is one of the critical outcomes when blood is exposed to
elevated shear stress. Excessively activated platelets in the circulation can lead to thrombus …

Multi‐objective genetic algorithm assisted by an artificial neural network metamodel for shape optimization of a centrifugal blood pump

B Ghadimi, A Nejat, SA Nourbakhsh… - Artificial organs, 2019 - Wiley Online Library
A centrifugal blood pump is a common type of the pump used as a left ventricular assist
device (LVAD) in the medical industries. The reduction of the LVADs hemolysis level to …

Probabilistic CFD analysis on the flow field and performance of the FDA centrifugal blood pump

R Mohammadi, MS Karimi, M Raisee… - Applied Mathematical …, 2022 - Elsevier
The present study is set out to systematically investigate the combined impact of operational,
geometrical, and model uncertainties on the hemodynamics and performance …

Shape optimization of a centrifugal blood pump by coupling CFD with metamodel-assisted genetic algorithm

B Ghadimi, A Nejat, SA Nourbakhsh… - Journal of Artificial Organs, 2019 - Springer
A centrifugal blood pump is a common type of pump used as a left ventricular assist device
in the medical industries. Therefore, the improvement of the device bio-compatibility to …

Computational analysis of flow structures in turbulent ventricular blood flow associated with mitral valve intervention

J Kronborg, F Svelander, S Eriksson-Lidbrink… - Frontiers in …, 2022 - frontiersin.org
Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis
events due to a modified blood flow in the heart, and thereby a change in the mechanical …