[HTML][HTML] Alzheimer's disease, obesity, and type 2 diabetes: focus on common neuroglial dysfunctions (critical review and new data on human brain and models)
A Toledano, A Rodríguez-Casado, MI Älvarez… - Brain Sciences, 2024 - mdpi.com
Background/Objectives. Obesity, type 2 diabetes (T2D), and Alzheimer's disease (AD) are
pathologies that affect millions of people worldwide. They have no effective therapy and are …
pathologies that affect millions of people worldwide. They have no effective therapy and are …
[HTML][HTML] From Brain to Muscle: The Role of Muscle Tissue in Neurodegenerative Disorders
Simple Summary Neurodegenerative diseases (NDs), like amyotrophic lateral sclerosis
(ALS), Alzheimer's disease (AD), and Parkinson's disease (PD), mainly impact the central …
(ALS), Alzheimer's disease (AD), and Parkinson's disease (PD), mainly impact the central …
[HTML][HTML] Mechanistic insights into the potential role of dietary polyphenols and their nanoformulation in the management of Alzheimer's disease
Alzheimer's disease (AD) is a very common neurodegenerative disorder associated with
memory loss and a progressive decline in cognitive activity. The two major …
memory loss and a progressive decline in cognitive activity. The two major …
Role of Flavonoids in Mitigating the Pathological Complexities and Treatment Hurdles in Alzheimer's Disease
With the passage of time, people step toward old age and become more prone to several
diseases associated with the age. One such is Alzheimer's disease (AD) which results into …
diseases associated with the age. One such is Alzheimer's disease (AD) which results into …
[HTML][HTML] Phytotherapy in Alzheimer's Disease—A Narrative Review
J Piekarz, N Picheta, O Burdan, M Kurek… - Biomedicines, 2024 - mdpi.com
Alzheimer's disease (AD) affects 50–70% of patients with dementia, making it the leading
cause of dementia. The condition is classified as a neurodegenerative, progressive and …
cause of dementia. The condition is classified as a neurodegenerative, progressive and …
Investigating the Potential Therapeutic Mechanisms of Puerarin in Neurological Diseases
Plants and their derived phytochemicals have a long history of treating a wide range of
illnesses for several decades. They are believed to be the origin of a diverse array of …
illnesses for several decades. They are believed to be the origin of a diverse array of …
Cross-scale targeted remodeling of neurovascular and neurometabolic coupling in Alzheimer's disease by natural self-assembled SIRT1 activator
D Zhao, F Yang, Y Liu, M Cheng, Z Chen, C Ye… - Nano Today, 2024 - Elsevier
Chronic neuromicrovascular dysfunction and its induced multifaceted neuropathology
involving the interaction of cellular differential pathogenic mechanisms pose challenges to …
involving the interaction of cellular differential pathogenic mechanisms pose challenges to …
Inflammatory signaling pathways in Alzheimer's disease: Mechanistic insights and possible therapeutic interventions
The complex pathophysiology of Alzheimer's disease (AD) poses challenges for the
development of therapies. Recently, neuroinflammation has been identified as a key …
development of therapies. Recently, neuroinflammation has been identified as a key …
Unveiling the Involvement of Herpes Simplex Virus-1 in Alzheimer's Disease: Possible Mechanisms and Therapeutic Implications
Viruses pose a significant challenge and threat to human health, as demonstrated by the
current COVID-19 pandemic. Neurodegeneration, particularly in the case of Alzheimer's …
current COVID-19 pandemic. Neurodegeneration, particularly in the case of Alzheimer's …
[HTML][HTML] Polyphenols from rose pepper spice: LC-MS/MS characterization and therapeutic potential in diabetes mellitus management
This study investigates the potential of polyphenols extracted from rose pepper in regulating
diabetes mellitus and associated complications, including cardiovascular issues, lipid profile …
diabetes mellitus and associated complications, including cardiovascular issues, lipid profile …