Effect of semaglutide versus other glucagon-like peptide-1 receptor agonists on cardio-metabolic risk factors in patients with type 2 diabetes: A systematic review and …

D Patoulias, DS Popovic, AP Stoian, A Janez… - Journal of Diabetes and …, 2023‏ - Elsevier
Introduction Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as a
cornerstone treatment for type 2 diabetes mellitus (T2DM). The aim of the present meta …

Efficacy and tolerability of the Subcutaneous Semaglutide for type 2 Diabetes patients: an updated systematic review and meta-analysis

S Hu, X Su, G Fan - Diabetology & Metabolic Syndrome, 2023‏ - Springer
Objectives To update and assess the efficacy and tolerability of once weekly subcutaneous
semaglutide in patients with type 2 diabetes (T2D). Materials and methods PubMed, Science …

Cardiovascular risk reduction with once-weekly semaglutide in subjects with type 2 diabetes: a post hoc analysis of gender, age, and baseline CV risk profile in the …

LA Leiter, SC Bain, I Hramiak, E Jódar… - Cardiovascular …, 2019‏ - Springer
Background The SUSTAIN 6 trial demonstrated that once-weekly semaglutide (0.5 and 1.0
mg) significantly reduced major adverse cardiovascular (CV) events (MACE) vs placebo in …

Incorporating and interpreting regulatory guidance on estimands in diabetes clinical trials: the PIONEER 1 randomized clinical trial as an example

VR Aroda, T Saugstrup, JB Buse… - Diabetes, Obesity …, 2019‏ - Wiley Online Library
Regulatory guidelines describe the use of estimands in designing and conducting clinical
trials. Estimands ensure alignment of the objectives with the design, conduct and analysis of …

Effects of glucagon-like peptide 1 receptor agonists on comorbidities in older patients with diabetes mellitus

OF Onoviran, D Li, S Toombs Smith… - … advances in chronic …, 2019‏ - journals.sagepub.com
Elderly patients with diabetes are at high risk of polypharmacy because of multiple
coexisting diseases and syndromes. Polypharmacy increases the risk of drug–drug and …

The cost-effectiveness analysis of semaglutide for the treatment of adult and adolescent patients with overweight and obesity: a systematic review

AS Asiabar, MA Rezaei, D Jafarzadeh, S Rajaei… - European Journal of …, 2024‏ - Springer
Purpose The present study aimed to systematically collect and synthesize available cost-
effectiveness studies of semaglutide in patients with obesity or overweight in comparison …

[HTML][HTML] Obesity management for the treatment of type 2 diabetes

AE Rothberg, JD Ard, KA Gudzune… - Diabetes in America …, 2024‏ - ncbi.nlm.nih.gov
Interventions to address obesity are recommended as treatments for type 2 diabetes. In this
article, nationally representative data are used to describe behavioral, pharmacologic, and …

[HTML][HTML] Weekly semaglutide vs. liraglutide efficacy profile: a network meta-analysis

HA Alsugair, IF Alshugair, TJ Alharbi, AM Bin Rsheed… - Healthcare, 2021‏ - mdpi.com
Introduction: Glucagon-like peptide 1 receptor agonist (GLP-1 RA) is a class of
hypoglycemic medications. Semaglutide once-weekly (QW) and liraglutide once-daily (OD) …

Do GLP‐1RAs and SGLT‐2is reduce cardiovascular events in black patients with type 2 diabetes? A systematic review and meta‐analysis

BM Mishriky, JR Powell, JA Wittwer… - Diabetes, Obesity …, 2019‏ - Wiley Online Library
Aims While recent cardiovascular safety trials (CVST) concerning newer diabetes
medications included mostly white participants, results are being generalized to all races in …

The cost-effectiveness of once-weekly semaglutide compared with other GLP-1 receptor agonists in type 2 Diabetes: a systematic literature review

Z Ruan, L Yang, H Shi, X Yue, Y Wang… - Expert review of …, 2021‏ - Taylor & Francis
Introduction: As a novel glucagon-like peptide-1receptor agonist (GLP-1 RA) for type 2
diabetes (T2D) treatment, the economic value of once-weekly semaglutide had been …