Role of Flavonoids in Mitigating the Pathological Complexities and Treatment Hurdles in Alzheimer's Disease

S Chib, BJ Dutta, R Chalotra, M Abubakar… - Phytotherapy …, 2024 - Wiley Online Library
With the passage of time, people step toward old age and become more prone to several
diseases associated with the age. One such is Alzheimer's disease (AD) which results into …

JNK inhibitor and ferroptosis modulator as possible therapeutic modalities in Alzheimer disease (AD)

S Zakaria, N Ibrahim, W Abdo, A E. El-Sisi - Scientific Reports, 2024 - nature.com
Alzheimer disease (AD) is among the most prevalent neurodegenerative diseases globally,
marked by cognitive and behavioral disruptions. Ferroptosis is a form of controlled cell death …

Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization

MR Ahmed, C Zheng, JL Dunning, MS Ahmed… - Cell Reports …, 2024 - cell.com
In rodents with unilateral ablation of neurons supplying dopamine to the striatum, chronic
treatment with the dopamine precursor L-DOPA induces a progressive increase of …

Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral and signaling plasticity in vivo

MR Ahmed, C Zheng, JL Dunning, MS Ahmed, C Ge… - …, 2023 - pmc.ncbi.nlm.nih.gov
In rodents with unilateral ablation of the substantia nigra neurons supplying dopamine to the
striatum, chronic treatment with the dopamine precursor L-DOPA or dopamine agonists …