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Theranostic fluorescent probes
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
Lipolysis: cellular mechanisms for lipid mobilization from fat stores
The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …
acids from fat stores in adipose tissue to generate energy has experienced major revisions …
Bioorthogonal chemistry
Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed
rapidly and selectively in biological environments without side reactions towards …
rapidly and selectively in biological environments without side reactions towards …
Goods and bads of the endocannabinoid system as a therapeutic target: lessons learned after 30 years
The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
[HTML][HTML] Greasing the wheels of the cancer machine: the role of lipid metabolism in cancer
Altered lipid metabolism is among the most prominent metabolic alterations in cancer.
Enhanced synthesis or uptake of lipids contributes to rapid cancer cell growth and tumor …
Enhanced synthesis or uptake of lipids contributes to rapid cancer cell growth and tumor …
[HTML][HTML] Membrane lipid composition: effect on membrane and organelle structure, function and compartmentalization and therapeutic avenues
D Casares, PV Escribá, CA Rosselló - International journal of molecular …, 2019 - mdpi.com
Biological membranes are key elements for the maintenance of cell architecture and
physiology. Beyond a pure barrier separating the inner space of the cell from the outer, the …
physiology. Beyond a pure barrier separating the inner space of the cell from the outer, the …
[HTML][HTML] Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention
With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …
Lipid droplets: platforms with multiple functions in cancer hallmarks
ALS Cruz, EA Barreto, NPB Fazolini, JPB Viola… - Cell death & …, 2020 - nature.com
Lipid droplets (also known as lipid bodies) are lipid-rich, cytoplasmic organelles that play
important roles in cell signaling, lipid metabolism, membrane trafficking, and the production …
important roles in cell signaling, lipid metabolism, membrane trafficking, and the production …
The adipocyte microenvironment and cancer
Many epithelial tumors grow in the vicinity of or metastasize to adipose tissue. As tumors
develop, crosstalk between adipose tissue and cancer cells leads to changes in adipocyte …
develop, crosstalk between adipose tissue and cancer cells leads to changes in adipocyte …
Morbidity and mortality associated with obesity
M Abdelaal, CW le Roux… - Annals of translational …, 2017 - pmc.ncbi.nlm.nih.gov
Obesity and its repercussions constitute an important source of morbidity, impaired quality of
life and its complications can have a major bearing on life expectancy. The present article …
life and its complications can have a major bearing on life expectancy. The present article …