Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - journals.asm.org
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Aspergillosis: epidemiology, diagnosis, and treatment

J Cadena, GR Thompson… - Infectious Disease Clinics, 2021 - id.theclinics.com
Aspergillosis refers to a spectrum of illness that is dependent on host factors and the
immunologic response. Noninvasive forms include allergic bronchopulmonary aspergillosis …

[HTML][HTML] Using inorganic nanoparticles to fight fungal infections in the antimicrobial resistant era

T Huang, X Li, M Maier, NM O'Brien-Simpson… - Acta Biomaterialia, 2023 - Elsevier
Fungal infections pose a serious threat to human health and livelihoods. The number and
variety of clinically approved antifungal drugs is very limited, and the emergence and rapid …

The global problem of antifungal resistance: prevalence, mechanisms, and management

DS Perlin, R Rautemaa-Richardson… - The Lancet infectious …, 2017 - thelancet.com
All serious fungal infections need appropriate antifungal therapy for successful patient
outcome. Only a few classes of antifungal drugs are available, so the emergence of …

Consensus guidelines for the diagnosis and management of invasive aspergillosis, 2021

AP Douglas, OC Smibert, A Bajel… - Internal Medicine …, 2021 - Wiley Online Library
Invasive aspergillosis (IA) in haematology/oncology patients presents as primary infection or
breakthrough infection, which can become refractory to antifungal treatment and has a high …

Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium

A Arastehfar, T Gabaldón, R Garcia-Rubio, JD Jenks… - Antibiotics, 2020 - mdpi.com
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …

[HTML][HTML] Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline

AJ Ullmann, JM Aguado, S Arikan-Akdagli… - Clinical Microbiology …, 2018 - Elsevier
Abstract The European Society for Clinical Microbiology and Infectious Diseases, the
European Confederation of Medical Mycology and the European Respiratory Society Joint …

Invasive aspergillosis in solid‐organ transplant recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

S Husain, JF Camargo - Clinical transplantation, 2019 - Wiley Online Library
These updated AST‐IDCOP guidelines provide information on epidemiology, diagnosis, and
management of Aspergillus after organ transplantation. Aspergillus is the most common …

Emerging threats in antifungal-resistant fungal pathogens

D Sanglard - Frontiers in medicine, 2016 - frontiersin.org
The use of antifungal drugs in the therapy of fungal diseases can lead to the development of
antifungal resistance. Resistance has been described for virtually all antifungal agents in …

Azole Resistance in Aspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?

PE Verweij, A Chowdhary… - Clinical Infectious …, 2016 - academic.oup.com
Azole resistance in Aspergillus fumigatus has emerged as a global health problem.
Although the number of cases of azole-resistant aspergillosis is still limited, resistance …