The treatment of advanced renal cell carcinoma (RCC) has evolved dramatically over the
past 30 years, as has a better understanding of the biology of the disease, knowledge of …

Fumarate hydratase (FH)-deficient renal cell carcinoma (FHdRCC) is a rare aggressive
subtype of RCC caused by a germline or sporadic loss-of-function mutation in the FH gene …

Purpose: Fumarate hydratase–deficient renal cell carcinoma (FH-deficient RCC) is a rare
but lethal subtype of RCC. Little is known about the genomic profile of FH-deficient RCC …

Clear cell renal cell carcinoma (ccRCC) is the most representative subtype of renal cancer.
CircRNA acts as a kind of ceRNA to play a role in regulating microRNA (miRNA) in many …

Background FH-deficient renal cell carcinoma (RCC) is a rare and exceptionally aggressive
RCC subtype. There is currently limited understanding of the molecular alterations …

In vitro cell-line cytotoxicity is widely used in the experimental studies of potential
antineoplastic agents and evaluation of safety in drug discovery. In silico estimation of …

Abstract Purpose Fumarate hydratase–deficient (FHdef) renal cell carcinoma (RCC) is a rare
entity associated with the hereditary leiomyomatosis and RCC syndrome with no standard …

Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a rare autosomal dominant
disorder that results from a germline mutation in the fumarate hydratase gene (FH) …

Non-clear cell renal cell carcinoma (nccRCC) is an entity comprised of a heterogeneous
constellation of RCC subtypes. Genomic profiling has broadened our understanding of …

Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is a rare autosomal dominant
hereditary cancer syndrome characterized by a predisposition to cutaneous leiomyomas …