Multidrug resistance in Escherichia coli has become a worrying issue that is increasingly
observed in human but also in veterinary medicine worldwide. E. coli is intrinsically …

The treatment of bacterial infections suffers from two major problems: spread of multidrug-
resistant (MDR) or extensively drug-resistant (XDR) pathogens and lack of development of …

Fosfomycin has been used for the treatment of infections due to susceptible and multidrug-
resistant (MDR) bacteria. It inhibits bacterial cell wall synthesis through a unique mechanism …

The role of farm animals in the emergence and dissemination of both AMR bacteria and their
resistance determinants to humans is poorly understood and controversial. Here, we …

The long-used antibiotic fosfomycin has recently been re-evaluated as a potential regimen
for treating extended-spectrum β-lactamases (ESBLs) and carbapenem-resistant …

Since around the 2000s, Escherichia coli (E. coli) resistant to both oxyimino-cephalosporins
and fluoroquinolones has remarkably increased worldwide in clinical settings. The kind of E …

There are challenges regarding increased global rates of microbial resistance and the
emergence of new mechanisms that result in microorganisms becoming resistant to …

Antimicrobial resistance is well-known to be a global health and development threat. Due to
the decrease of effective antimicrobials, re-evaluation in clinical practice of old antibiotics, as …

Objectives The objectives of this study were to elucidate the genetic context of a novel
plasmid-mediated fosA variant, fosA6, conferring fosfomycin resistance and to characterize …

Increasing numbers of multi-resistant Escherichia (E.) coli from clinical specimens
emphasize the importance of monitoring of their resistance profiles for proper treatment …