As an efficient class of hydrogel-based therapeutic drug delivery systems, deoxyribonucleic
acid (DNA) hydrogels (particularly DNA nanogels) have attracted massive attention in the …

One of the most important topics in molecular biology is the genetic stability of DNA. One
threat to this stability is proton transfer along the hydrogen bonds of DNA that could lead to …

DNA (2′-deoxyribonucleic acid) and RNA (ribonucleic acid) play diverse functional roles in
biology and disease. Despite being comprised primarily of only four cognate nucleobases …

Favipiravir is an important selective antiviral against RNA-based viruses, and currently, it is
being repurposed as a potential drug for the treatment of COVID-19. This type of chemical …

In this work hydrogen bonding in a diverse set of 36 unnatural and the three natural Watson
Crick base pairs adenine (A)–thymine (T), adenine (A)–uracil (U) and guanine (G)–cytosine …

In the present letter, we investigate the double proton transfer (DPT) tautomerization process
in guanine–cytosine (GC) DNA base pairs. In particular, we study the influence of the …

The misincorporation of a noncomplementary DNA base in the polymerase active site is a
critical source of replication errors that can lead to genetic mutations. In this work, we model …

Proton transfer between the DNA bases can lead to mutagenic Guanine-Cytosine tautomers.
Over the past several decades, a heated debate has emerged over the biological impact of …

We report on a vibrational study of the guanine–cytosine dimer tautomers using state-of-the-
art quasiclassical trajectory and semiclassical vibrational spectroscopy. The latter includes …

Metal ions play vital roles in the electron transfer between biological molecules in humans,
animals, and plants. However, the electron transfer between metal ions and nucleic acids …