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DNA hydrogels and nanogels for diagnostics, therapeutics, and theragnostics of various cancers
I Zare, R Taheri-Ledari, F Esmailzadeh, MM Salehi… - Nanoscale, 2023 - pubs.rsc.org
As an efficient class of hydrogel-based therapeutic drug delivery systems, deoxyribonucleic
acid (DNA) hydrogels (particularly DNA nanogels) have attracted massive attention in the …
acid (DNA) hydrogels (particularly DNA nanogels) have attracted massive attention in the …
[HTML][HTML] Quantum biology and the potential role of entanglement and tunneling in non-targeted effects of ionizing radiation: a review and proposed model
BFE Matarèse, A Rusin, C Seymour… - International journal of …, 2023 - mdpi.com
It is well established that cells, tissues, and organisms exposed to low doses of ionizing
radiation can induce effects in non-irradiated neighbors (non-targeted effects or NTE), but …
radiation can induce effects in non-irradiated neighbors (non-targeted effects or NTE), but …
An open quantum systems approach to proton tunnelling in DNA
One of the most important topics in molecular biology is the genetic stability of DNA. One
threat to this stability is proton transfer along the hydrogen bonds of DNA that could lead to …
threat to this stability is proton transfer along the hydrogen bonds of DNA that could lead to …
Environmental and Nuclear Quantum Effects on Double Proton Transfer in the Guanine–Cytosine Base Pair
In the present letter, we investigate the double proton transfer (DPT) tautomerization process
in guanine–cytosine (GC) DNA base pairs. In particular, we study the influence of the …
in guanine–cytosine (GC) DNA base pairs. In particular, we study the influence of the …
Quantum tunnelling effects in the Guanine-Thymine Wobble misincorporation via tautomerism
The misincorporation of a noncomplementary DNA base in the polymerase active site is a
critical source of replication errors that can lead to genetic mutations. In this work, we model …
critical source of replication errors that can lead to genetic mutations. In this work, we model …
Role and potential of the semi-classical/-quantum mechanism of the extracellular environment and cell envelope in Direct Interspecies Electron Transfer (DIET)-driven …
The extracellular electron transfer (EET) capability of Methanosarcina spp. in direct
interspecies electron transfer (DIET) has profoundly increased our understanding of …
interspecies electron transfer (DIET) has profoundly increased our understanding of …
Hydrogen bonding in natural and unnatural base pairs—a local vibrational mode study
N Beiranvand, M Freindorf, E Kraka - Molecules, 2021 - mdpi.com
In this work hydrogen bonding in a diverse set of 36 unnatural and the three natural Watson
Crick base pairs adenine (A)–thymine (T), adenine (A)–uracil (U) and guanine (G)–cytosine …
Crick base pairs adenine (A)–thymine (T), adenine (A)–uracil (U) and guanine (G)–cytosine …
Proton transfer during DNA strand separation as a source of mutagenic guanine-cytosine tautomers
Proton transfer between the DNA bases can lead to mutagenic Guanine-Cytosine tautomers.
Over the past several decades, a heated debate has emerged over the biological impact of …
Over the past several decades, a heated debate has emerged over the biological impact of …
Tautomerism and rotamerism of favipiravir and halogenated analogues in solution and in the solid state
Favipiravir is an important selective antiviral against RNA-based viruses, and currently, it is
being repurposed as a potential drug for the treatment of COVID-19. This type of chemical …
being repurposed as a potential drug for the treatment of COVID-19. This type of chemical …
Structural insights into tautomeric dynamics in nucleic acids and in antiviral nucleoside analogs
DNA (2′-deoxyribonucleic acid) and RNA (ribonucleic acid) play diverse functional roles in
biology and disease. Despite being comprised primarily of only four cognate nucleobases …
biology and disease. Despite being comprised primarily of only four cognate nucleobases …