MicroRNA as potential biomarkers of platelet function on antiplatelet therapy: a review

P Czajka, A Fitas, D Jakubik, C Eyileten… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) are small, non-coding RNAs, able to regulate cellular functions by
specific gene modifications. Platelets are the major source for circulating miRNAs, with …

Platelets and the atherosclerotic process: an overview of new markers of platelet activation and reactivity, and their implications in primary and secondary prevention

M Nardin, M Verdoia, D Cao, S Nardin, E Kedhi… - Journal of Clinical …, 2023 - mdpi.com
The key role played by platelets in the atherosclerosis physiopathology, especially in the
acute setting, is ascertained: they are the main actors during thrombus formation and, thus …

The role of miRNAs in regulation of platelet activity and related diseases-a bioinformatic analysis

Z Wicik, P Czajka, C Eyileten, A Fitas, M Wolska… - Platelets, 2022 - Taylor & Francis
MicroRNAs (miRNAs) are small, non-coding RNAs, able to regulate cellular functions by
induction of mRNA degradation and post-transcriptional repression of gene expression …

Circulating and platelet MicroRNAs in cardiovascular risk assessment and antiplatelet therapy monitoring

G Procyk, D Klimczak-Tomaniak, G Sygitowicz… - Journal of Clinical …, 2022 - mdpi.com
Micro-ribonucleic acids (microRNAs) are small molecules that take part in the regulation of
gene expression. Their function has been extensively investigated in cardiovascular …

Platelet function and maturity and related microRNA expression in whole blood in patients with ST-segment elevation myocardial infarction

OB Pedersen, AM Hvas, L Pasalic… - Thrombosis and …, 2024 - thieme-connect.com
Background Reduced effect of antiplatelet therapy has been reported in patients with ST-
segment elevation myocardial infarction (STEMI). MicroRNAs (miRs) may influence platelet …

MicroRNA as biomarkers for platelet function and maturity in patients with cardiovascular disease

OB Pedersen, EL Grove, SD Kristensen… - Thrombosis and …, 2022 - thieme-connect.com
Patients with cardiovascular disease (CVD) are at increased risk of suffering myocardial
infarction. Platelets are key players in thrombus formation and, therefore, antiplatelet therapy …

Factors associated with platelet activation-recent pharmaceutical approaches

P Theofilis, M Sagris, E Oikonomou… - International Journal of …, 2022 - mdpi.com
Platelets are at the forefront of human health and disease following the advances in their
research presented in past decades. Platelet activation, their most crucial function, although …

Circulating microRNAs as biomarkers and mediators of platelet activation

C Gutmann, M Mayr - Platelets, 2022 - Taylor & Francis
Platelets are essential mediators of physiological hemostasis and pathological thrombosis.
Currently available tests and markers of platelet activation did not prove successful in …

MicroRNAs: circulating biomarkers for the early detection of imperceptible cancers via biosensor and machine-learning advances

GAD Metcalf - Oncogene, 2024 - nature.com
This review explores the topic of microRNAs (miRNAs) for improved early detection of
imperceptible cancers, with potential to advance precision medicine and improve patient …

Alteration of circulating platelet-related and diabetes-related microRNAs in individuals with type 2 diabetes mellitus: a stepwise hypoglycaemic clamp study

C Eyileten, Z Wicik, D Keshwani, F Aziz… - Cardiovascular …, 2022 - Springer
Background In patients with type 2 diabetes mellitus (T2DM) an association between severe
hypoglycaemic episodes and the risk of cardiovascular (CV) morbidity and mortality has …