Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor
problems for people with a detrimental effect on the functioning of the nervous system. In …

There are> 18 distinct disease-modifying therapy (DMT) options covering 10 mechanisms of
action currently approved by the US Food and Drug Administration for the treatment of …

Objective The radiologically isolated syndrome (RIS) represents the earliest detectable pre‐
clinical phase of multiple sclerosis (MS). This study evaluated the impact of therapeutic …

Multiple sclerosis is a complex, autoimmune-mediated disease of the central nervous
system characterized by inflammatory demyelination and axonal/neuronal damage. The …

A prodrome is an early set of signs or symptoms that indicate the onset of a disease before
more typical symptoms develop. Prodromal stages are well recognized in some neurological …

In the past decade, changes have occurred in the spectrum of multiple sclerosis courses.
The natural history of multiple sclerosis appears milder from the first sign of demyelinating …

In the majority of cases, multiple sclerosis (MS) is characterized by reversible episodes of
neurological dysfunction, often followed by irreversible clinical disability. Accurate diagnostic …

Importance Although magnetic resonance imaging (MRI) is useful for monitoring disease
dissemination in space and over time and excluding multiple sclerosis (MS) mimics, there …

Objectives Magnetic resonance imaging (MRI) is an important tool for diagnosis and
monitoring of disease course in multiple sclerosis (MS). However, its prognostic value for …

Background Easily accessible biomarkers enabling the identification of those patients with
multiple sclerosis (MS) who will accumulate irreversible disability in the long term are …