The understanding that changes in microbiome composition can influence chronic human
diseases and the efficiency of therapies has driven efforts to develop microbiota-centred …

The human intestinal microbiome has coevolved with its host to establish a stable
homeostatic relationship with hallmark features of mutualistic symbioses, yet the mechanistic …

Despite recent progress in our understanding of the association between the gut
microbiome and inflammatory bowel disease (IBD), the role of microbiome biomarkers in …

Ulcerative colitis (UC) is a debilitating inflammatory bowel disease characterized by
intestinal inflammation, barrier dysfunction, and dysbiosis, with limited treatment options …

Commensal microorganisms in the human gut produce numerous metabolites by using
small molecules derived from the host or diet as precursors. Host or dietary lipid molecules …

Metabolic derivatives of numerous microorganisms inhabiting the human gut can participate
in physiological activities and immune status of the lungs through the gut-lung axis. The …

Polyunsaturated fatty acids (PUFAs) are dietary components participating in
neurotransmission and cell signaling. Pollen is a source of PUFAs for honeybees, and …

This study explored the structure and biological activities of a novel polysaccharide, PRY1–
1, isolated from red yeast rice (RYR) through solid-state fermentation and biotransformation …

A key aspect of nutrient absorption is the exquisite division of labour across the length of the
small intestine, with individual nutrients taken up at different proximal: distal positions. For …

Understanding the role of the microbiome in inflammatory diseases requires the
identification of microbial effector molecules. We established an approach to link disease …