Photodynamic and photothermal therapies: synergy opportunities for nanomedicine

M Overchuk, RA Weersink, BC Wilson, G Zheng - ACS nano, 2023 - ACS Publications
Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to
eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen …

Rational design of biomaterials to potentiate cancer thermal therapy

Y Zhu, Q Li, C Wang, Y Hao, N Yang, M Chen… - Chemical …, 2023 - ACS Publications
Cancer thermal therapy, also known as hyperthermia therapy, has long been exploited to
eradicate mass lesions that are now defined as cancer. With the development of …

Recent advances in contrast-enhanced photoacoustic imaging: overcoming the physical and practical challenges

W Choi, B Park, S Choi, D Oh, J Kim, C Kim - Chemical Reviews, 2023 - ACS Publications
For decades now, photoacoustic imaging (PAI) has been investigated to realize its potential
as a niche biomedical imaging modality. Despite its highly desirable optical contrast and …

The emerging role of photoacoustic imaging in clinical oncology

L Lin, LV Wang - Nature Reviews Clinical Oncology, 2022 - nature.com
Clinical oncology can benefit substantially from imaging technologies that reveal
physiological characteristics with multiscale observations. Complementing conventional …

Molecular radio afterglow probes for cancer radiodynamic theranostics

J Huang, L Su, C Xu, X Ge, R Zhang, J Song, K Pu - Nature Materials, 2023 - nature.com
X-ray-induced afterglow and radiodynamic therapy tackle the tissue penetration issue of
optical imaging and phototherapy. However, inorganic nanophosphors used in this therapy …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020 - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …

Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …

Supramolecular cancer nanotheranostics

J Zhou, L Rao, G Yu, TR Cook, X Chen… - Chemical Society …, 2021 - pubs.rsc.org
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

Advances in nanomaterial-mediated photothermal cancer therapies: toward clinical applications

HS Han, KY Choi - Biomedicines, 2021 - mdpi.com
Photothermal therapy (PTT) has attracted extensive research attention as a noninvasive and
selective treatment strategy for numerous cancers. PTT functions via photothermal effects …

Renal clearable polyfluorophore nanosensors for early diagnosis of cancer and allograft rejection

J Huang, X Chen, Y Jiang, C Zhang, S He, H Wang… - Nature Materials, 2022 - nature.com
Optical nanoparticles are promising diagnostic tools; however, their shallow optical imaging
depth and slow clearance from the body have impeded their use for in vivo disease …