Age-associated B cells
The age-associated B cell subset has been the focus of increasing interest over the last
decade. These cells have a unique cell surface phenotype and transcriptional signature …
decade. These cells have a unique cell surface phenotype and transcriptional signature …
NF-kB's contribution to B cell fate decisions
NF-κB signaling is essential to an effective innate and adaptive immune response. Many
immune-specific functional and developmental outcomes depend in large on NF-κB. The …
immune-specific functional and developmental outcomes depend in large on NF-κB. The …
B cell development pathways
RR Hardy, K Hayakawa - Annual review of immunology, 2001 - annualreviews.org
B cell development is a highly regulated process whereby functional peripheral subsets are
produced from hematopoietic stem cells, in the fetal liver before birth and in the bone …
produced from hematopoietic stem cells, in the fetal liver before birth and in the bone …
Identification and characterization of circulating human transitional B cells
GP Sims, R Ettinger, Y Shirota, CH Yarboro, GG Illei… - Blood, 2005 - ashpublications.org
Murine B-cell development begins in bone marrow and results in the generation of immature
transitional B cells that transit to the spleen to complete their maturation. It remains unclear …
transitional B cells that transit to the spleen to complete their maturation. It remains unclear …
BAFF mediates survival of peripheral immature B lymphocytes
B cell maturation is a very selective process that requires finely tuned differentiation and
survival signals. B cell activation factor from the TNF family (BAFF) is a TNF family member …
survival signals. B cell activation factor from the TNF family (BAFF) is a TNF family member …
[HTML][HTML] Defective B cell development and function in Btk-deficient mice
Mutations in the Bruton's tyrosine kinase (Btk) gene have been linked to severe early B cell
developmental blocks in human X-linked agammaglobulinemia (XLA), and to milder B cell …
developmental blocks in human X-linked agammaglobulinemia (XLA), and to milder B cell …
Neutralizing antiviral B cell responses
▪ Abstract Neutralizing antiviral B cell responses differ in various aspects from the many
usually measured B cell responses specific for protein in adjuvants. In particular, such …
usually measured B cell responses specific for protein in adjuvants. In particular, such …
Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation
Although immature/transitional peripheral B cells may remain susceptible to selection
pressures before full maturation, the nature and timing of these selection events remain …
pressures before full maturation, the nature and timing of these selection events remain …
Signaling by the tumor necrosis factor receptor superfamily in B‐cell biology and disease
RC Rickert, J Jellusova, AV Miletic - Immunological reviews, 2011 - Wiley Online Library
Members of the tumor necrosis factor receptor superfamily (TNFRSF) participate prominently
in B‐cell maturation and function. In particular, B‐cell activating factor belonging to the TNF …
in B‐cell maturation and function. In particular, B‐cell activating factor belonging to the TNF …
Marginal zone B cells
▪ Abstract Our views regarding the origins and functions of splenic marginal zone B cells
have changed considerably over the past few years. Perspectives regarding the …
have changed considerably over the past few years. Perspectives regarding the …