Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

The past 20 years have witnessed ever-growing evidence that the mechanical properties of
biological tissues, from nanoscale to macroscale dimensions, are fundamental for cellular …

Hydrogels are widely used for wound healing applications due to their similarity to the native
extracellular matrix (ECM) and ability to provide a moist environment. However, lack of …

Traditional hydrogels are strong candidates for biomedical applications; however, they may
suffer from drawbacks such as weak mechanics, static properties, and an inability to fully …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Corneal transplantation constitutes one of the leading treatments for severe cases of loss of
corneal function. Due to its limitations, a concerted effort has been made by tissue engineers …

The cellular and molecular basis of stromal cell recruitment, activation and crosstalk in
carcinomas is poorly understood, limiting the development of targeted anti-stromal …

Excessive scar formation has adverse physiological and psychological effects on patients;
therefore, a therapeutic strategy for rapid wound healing and reduced scar formation is …

Hydrogel-based wound dressings are ideal materials as they could provide a moist
environment to promote wound healing. Silk sericin is a natural macromolecular protein …