The brain is vulnerable to excessive oxidative insults because of its abundant lipid content,
high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) …

Alzheimer's disease (AD) is characterized by the progressive degeneration of neuronal
cells. With the increase in aged population, there is a prevalence of irreversible …

Coenzyme Q 10 (CoQ 10) is a ubiquitous factor present in cell membranes and
mitochondria, both in its reduced (ubiquinol) and oxidized (ubiquinone) forms. Its levels are …

Acute central nervous system (CNS) injuries, such as stroke, traumatic brain injury (TBI), and
spinal cord injury (SCI) present a grave health care challenge worldwide due to high …

Neurological disorders affect the nervous system. Biochemical, structural, or electrical
abnormalities in the spinal cord, brain, or other nerves lead to different symptoms, including …

Gulf War illness (GWI) is an important exemplar of environmentally-triggered chronic
multisymptom illness, and a potential model for accelerated aging. Inflammation is the main …

Cerebrovascular diseases (CBD) are one of the most dangerous complications of
atherosclerosis. The clinical consequences of CBD deeply impact quality of life and the …

Evidence shows that exogenous CoQ10 supplementation may potentially attenuate
oxidative stress status. However, its effective dose and evidence certainty require further …