Global status of azithromycin and erythromycin resistance rates in Neisseria gonorrhoeae: a systematic review and meta-analysis

Z Lu, DA Tadi, J Fu, K Azizian… - The Yale journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Background: The widespread development of antibiotic resistance or decreased
susceptibility in Neisseria gonorrhoeae (NG) infection is a global and significant human …

A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch

L Sánchez-Busó, CA Yeats, B Taylor, RJ Goater… - Genome medicine, 2021 - Springer
Abstract Background Antimicrobial-resistant (AMR) Neisseria gonorrhoeae is an urgent
threat to public health, as strains resistant to at least one of the two last-line antibiotics used …

Applications of genomics to slow the spread of multidrug‐resistant Neisseria gonorrhoeae

TD Mortimer, YH Grad - Annals of the New York Academy of …, 2019 - Wiley Online Library
Infections with Neisseria gonorrhoeae, a sexually transmitted pathogen that causes
urethritis, cervicitis, and more severe complications, are increasing. Gonorrhea is typically …

Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data

AL Hicks, N Wheeler, L Sánchez-Busó… - PLoS computational …, 2019 - journals.plos.org
Prediction of antibiotic resistance phenotypes from whole genome sequencing data by
machine learning methods has been proposed as a promising platform for the development …

Bridging of Neisseria gonorrhoeae lineages across sexual networks in the HIV pre-exposure prophylaxis era

DA Williamson, EPF Chow, CL Gorrie… - Nature …, 2019 - nature.com
Whole genome sequencing (WGS) has been used to investigate transmission of Neisseria
gonorrhoeae, but to date, most studies have not combined genomic data with detailed …

Host adaptation and convergent evolution increases antibiotic resistance without loss of virulence in a major human pathogen

A Fajardo-Lubián, NL Ben Zakour, A Agyekum… - PLoS …, 2019 - journals.plos.org
As human population density and antibiotic exposure increase, specialised bacterial
subtypes have begun to emerge. Arising among species that are common commensals and …

Stably high azithromycin resistance and decreasing ceftriaxone susceptibility in Neisseria gonorrhoeae in 25 European countries, 2016

MJ Day, G Spiteri, S Jacobsson, N Woodford… - BMC infectious …, 2018 - Springer
Abstract Background The European Gonococcal Antimicrobial Surveillance Programme
(Euro-GASP) performs annual sentinel surveillance of Neisseria gonorrhoeae susceptibility …

[HTML][HTML] Prediction of antimicrobial minimal inhibitory concentrations for Neisseria gonorrhoeae using machine learning models

M Yasir, AM Karim, SK Malik, AA Bajaffer… - Saudi Journal of …, 2022 - Elsevier
The lowest concentration of an antimicrobial agent that can inhibit the visible growth of a
microorganism after overnight incubation is called as minimum inhibitory concentration …

[HTML][HTML] Effectiveness of a group B outer membrane vesicle meningococcal vaccine in preventing hospitalization from gonorrhea in New Zealand: a retrospective …

J Paynter, F Goodyear-Smith, J Morgan, P Saxton… - Vaccines, 2019 - mdpi.com
Gonorrhea is a major global public health problem with emergence of multiple drug-resistant
strains with no effective vaccine. This retrospective cohort study aimed to estimate the …

Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae

K Yahara, KC Ma, TD Mortimer, K Shimuta… - Genome medicine, 2021 - Springer
Abstract Background Antimicrobial resistance in Neisseria gonorrhoeae is a global health
concern. Strains from two internationally circulating sequence types, ST-7363 and ST-1901 …