Local immune system in oviduct physiology and pathophysiology: attack or tolerance?

MA Marey, MS Yousef, R Kowsar, N Hambruch… - Domestic animal …, 2016 - Elsevier
The local immune system in the oviduct has a unique ability to deal with pathogens,
allogeneic spermatozoa, and the semi-allogeneic embryo. To achieve this, it seems likely …

Understanding the causes of variation in reproductive wastage among bulls

S Fair, P Lonergan - Animal, 2018 - cambridge.org
The ability to predict the fertility of bulls before semen is released into the field has been a
long-term objective of the animal breeding industry. However, the recent shift in the dairy …

Vaginal neutrophils eliminate sperm by trogocytosis

I Olivera-Valle, MC Latorre, M Calvo… - Human …, 2020 - academic.oup.com
STUDY QUESTION What is the vaginal polymorphonuclear (PMN) spermicidal mechanism
to reduce the excess of sperm? SUMMARY ANSWER We show that PMNs are very efficient …

Ovulatory follicular fluid induces sperm phagocytosis by neutrophils, but oviductal fluid around oestrus suppresses its inflammatory effect in the buffalo oviduct in vitro

MS Yousef, HH Abd‐Elhafeez… - Molecular …, 2019 - Wiley Online Library
We have recently shown that the conditioned media from bovine oviductal epithelial cell
culture suppress sperm phagocytosis by neutrophils, suggesting that the oviduct around …

A higher abundance of O-linked glycans confers a selective advantage to high fertile buffalo spermatozoa for immune-evasion from neutrophils

V Batra, K Dagar, S Nayak, A Kumaresan… - Frontiers in …, 2020 - frontiersin.org
The glycans on the plasma membrane of cells manifest as the glycocalyx, which serves as
an information-rich frontier that is directly in contact with its immediate milieu. The …

The role of neutrophil activation in determining the outcome of pregnancy and modulation by hormones and/or cytokines

S Hahn, P Hasler, L Vokalova… - Clinical & …, 2019 - academic.oup.com
Neutrophils are often exclusively considered as a first-line innate immune defence, able to
rapidly kill or trap pathogens and causing in case of over-activation tissue damage. In the …

Sensing sperm via maternal immune system: a potential mechanism for controlling microenvironment for fertility in the cow

MA Marey, M Aboul Ezz, I Akthar… - Journal of animal …, 2020 - academic.oup.com
Both the uterus and oviduct are functionally adapted to facilitate sperm transport, oocyte
fertilization, embryonic/fetal development, and deliver a calf. However, the mucosa of the …

An autoregressive logistic model to predict the reciprocal effects of oviductal fluid components on in vitro spermophagy by neutrophils in cattle

R Kowsar, B Keshtegar, MA Marey, A Miyamoto - Scientific Reports, 2017 - nature.com
After intercourse/insemination, large numbers of sperm are deposited in the female
reproductive tract (FRT), triggering a massive recruitment of neutrophils (PMNs) into the …

Bovine oviduct epithelial cells suppress the phagocytic activity of neutrophils towards sperm but not for bacteria in vitro: immunofluorescence and electron microscopic …

MA Marey, H Matsukawa, M Sasaki, MA Ezz… - 2020 - digitum.um.es
Previously, we reported that polymorpho-nuclear neutrophils (PMNs) are constantly existent
in the bovine oviduct fluid during the pre-ovulatory stage under physiological conditions …

Angiotensin II increases sperm phagocytosis by neutrophils in vitro: A possible physiological role in the bovine oviduct

MA Marey, MS Yousef, J Liu, K Morita… - Molecular …, 2016 - Wiley Online Library
This study aimed to investigate the possible effects of the vasoactive peptide angiotensin II
(ANG II), secreted by bovine oviduct epithelial cells, on the in vitro phagocytic activity of …