[HTML][HTML] Correlation between CSF and blood neurofilament light chain protein: a systematic review and meta-analysis
J Alagaratnam, S von Widekind… - BMJ neurology …, 2021 - ncbi.nlm.nih.gov
Objective To assess the overall pooled correlation coefficient estimate between
cerebrospinal fluid (CSF) and blood neurofilament light (NfL) protein. Methods We searched …
cerebrospinal fluid (CSF) and blood neurofilament light (NfL) protein. Methods We searched …
Molecular biomarkers and cognitive impairment in multiple sclerosis: state of the field, limitations, and future direction–a systematic review and meta-analysis
TD Rademacher, SG Meuth, H Wiendl, A Johnen… - Neuroscience & …, 2023 - Elsevier
Objective Multiple sclerosis (MS) is associated with cognitive impairment (CI) such as
slowed information processing speed (IPS). Currently, no immunocellular or molecular …
slowed information processing speed (IPS). Currently, no immunocellular or molecular …
Comparison of serum neurodegenerative biomarkers among hospitalized COVID‐19 patients versus non‐COVID subjects with normal cognition, mild cognitive …
Introduction Neurological complications among hospitalized COVID‐19 patients may be
associated with elevated neurodegenerative biomarkers. Methods Among hospitalized …
associated with elevated neurodegenerative biomarkers. Methods Among hospitalized …
Comparing glial fibrillary acidic protein (GFAP) in serum and plasma following mild traumatic brain injury in older adults
Objective: Identification and validation of blood-based biomarkers for the diagnosis and
prognosis of mild traumatic brain injury (mTBI) is of critical importance. There have been …
prognosis of mild traumatic brain injury (mTBI) is of critical importance. There have been …
Alzheimer blood biomarkers: practical guidelines for study design, sample collection, processing, biobanking, measurement and result reporting
X Zeng, Y Chen, A Sehrawat, J Lee, TK Lafferty… - Molecular …, 2024 - Springer
Abstract Alzheimer's disease (AD), the most common form of dementia, remains challenging
to understand and treat despite decades of research and clinical investigation. This might be …
to understand and treat despite decades of research and clinical investigation. This might be …
Effect of long-term storage on the reliability of blood biomarkers for Alzheimer's disease and neurodegeneration
CR Schubert, AJ Paulsen, AA Pinto… - Journal of …, 2022 - content.iospress.com
Background: Stored blood samples from longitudinal cohort studies may be useful for
studying biomarkers of preclinical Alzheimer's disease. Objective: This study aimed to …
studying biomarkers of preclinical Alzheimer's disease. Objective: This study aimed to …
Clinical peptidomics: advances in instrumentation, analyses, and applications
L Li, J Wu, CJ Lyon, L Jiang, TY Hu - BME frontiers, 2023 - spj.science.org
Extensive effort has been devoted to the discovery, development, and validation of
biomarkers for early disease diagnosis and prognosis as well as rapid evaluation of the …
biomarkers for early disease diagnosis and prognosis as well as rapid evaluation of the …
Tau kinetics in Alzheimer's disease
The cytoskeletal protein tau is implicated in the pathogenesis of Alzheimer's disease which
is characterized by intra-neuronal neurofibrillary tangles containing abnormally …
is characterized by intra-neuronal neurofibrillary tangles containing abnormally …
Serum neurofilament dynamics predicts cognitive progression in de novo Parkinson's disease
LZ Ma, C Zhang, H Wang, YH Ma… - Journal of …, 2021 - content.iospress.com
Background: Neurofilament light (NfL) can reflect the extent of neuron/axon damage, thus
providing an opportunity to examine the severity and progression of the diseases with such …
providing an opportunity to examine the severity and progression of the diseases with such …
Use of high-sensitivity digital ELISA improves the diagnostic performance of circulating brain-specific proteins for detection of traumatic brain injury during triage
Background: Historically, limited sensitivity associated with traditional immunoassay
methods has prevented the use of brain-specific proteins as blood biomarkers of traumatic …
methods has prevented the use of brain-specific proteins as blood biomarkers of traumatic …