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[HTML][HTML] Adult hippocampal neurogenesis in Alzheimer's disease: A roadmap to clinical relevance
Adult hippocampal neurogenesis (AHN) drops sharply during early stages of Alzheimer's
disease (AD), via unknown mechanisms, and correlates with cognitive status in AD patients …
disease (AD), via unknown mechanisms, and correlates with cognitive status in AD patients …
[HTML][HTML] Memory circuits in dementia: The engram, hippocampal neurogenesis and Alzheimer's disease
Here, we provide an in-depth consideration of our current understanding of engrams,
spanning from molecular to network levels, and hippocampal neurogenesis, in health and …
spanning from molecular to network levels, and hippocampal neurogenesis, in health and …
[HTML][HTML] Hesperidin improves memory function by enhancing neurogenesis in a mouse model of Alzheimer's disease
D Lee, N Kim, SH Jeon, MS Gee, YJ Ju, MJ Jung… - Nutrients, 2022 - mdpi.com
Alzheimer's disease (AD) is an irreversible neurodegenerative disease characterized by
memory and cognitive impairments. Neurogenesis, which is related to memory and cognitive …
memory and cognitive impairments. Neurogenesis, which is related to memory and cognitive …
Hippocampal-subfield microstructures and their relation to plasma biomarkers in Alzheimer's disease
Hippocampal subfields exhibit differential vulnerabilities to Alzheimer's disease-associated
pathology including abnormal accumulation of amyloid-β deposition and neurofibrillary …
pathology including abnormal accumulation of amyloid-β deposition and neurofibrillary …
Benefits of the neurogenic potential of melatonin for treating neurological and neuropsychiatric disorders
There are several neurological diseases under which processes related to adult brain
neurogenesis, such cell proliferation, neural differentiation and neuronal maturation, are …
neurogenesis, such cell proliferation, neural differentiation and neuronal maturation, are …
Insight into the role of adult hippocampal neurogenesis in aging and Alzheimer's disease
P Chen, ZL Guo, B Zhou - Ageing research reviews, 2023 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia and seriously affects the
quality of life of the elderly. Neurodegeneration is closely related to hippocampal dysfunction …
quality of life of the elderly. Neurodegeneration is closely related to hippocampal dysfunction …
Neural stem cells in the treatment of Alzheimer's disease: Current status, challenges, and future prospects
X Chen, S Jiang, R Wang, X Bao… - Journal of Alzheimer's …, 2023 - journals.sagepub.com
Alzheimer's disease (AD), a progressive dementia, is one of the world's most dangerous and
debilitating diseases. Clinical trial results of amyloid-β (Aβ) and tau regulators based on the …
debilitating diseases. Clinical trial results of amyloid-β (Aβ) and tau regulators based on the …
[HTML][HTML] Targeting impaired adult hippocampal neurogenesis in ageing by leveraging intrinsic mechanisms regulating neural stem cell activity
S Gillotin, V Sahni, T Lepko, MA Hanspal… - Ageing Research …, 2021 - Elsevier
Deficits in adult neurogenesis may contribute to the aetiology of many neurodevelopmental,
psychiatric and neurodegenerative diseases. Genetic ablation of neurogenesis provides …
psychiatric and neurodegenerative diseases. Genetic ablation of neurogenesis provides …
[HTML][HTML] Alzheimer's Disease: Challenges and a Therapeutic Opportunity to Treat It with a Neurotrophic Compound
N Baazaoui, K Iqbal - Biomolecules, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease with an insidious
onset and multifactorial nature. A deficit in neurogenesis and synaptic plasticity are …
onset and multifactorial nature. A deficit in neurogenesis and synaptic plasticity are …
Active constituent of Polygala tenuifolia attenuates cognitive deficits by rescuing hippocampal neurogenesis in APP/PS1 transgenic mice
X Wang, H **ao, Y Wu, L Kong, J Chen, J Yang… - … medicine and therapies, 2021 - Springer
Background Alzheimer's disease (AD) is the most common dementia worldwide, and there is
still no satisfactory drug or therapeutic strategy. Polygala tenuifolia is a traditional Chinese …
still no satisfactory drug or therapeutic strategy. Polygala tenuifolia is a traditional Chinese …