Poly (ethylene glycol) alternatives in biomedical applications

X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023‏ - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …

Poly (2-oxazoline) s based biomaterials: A comprehensive and critical update

T Lorson, MM Luebtow, E Wegener, MS Haider… - Biomaterials, 2018‏ - Elsevier
Abstract Poly (2-oxazoline) s have been investigated for decades as biomaterials.
Pioneering early work suggested that hydrophilic poly (2-oxazoline) s are comparable to …

Poly (2‐oxazoline) s: A comprehensive overview of polymer structures and their physical properties

M Glassner, M Vergaelen… - Polymer …, 2018‏ - Wiley Online Library
Abstract Poly (2‐oxazoline) s (PAOx) are of increasing importance for a wide range of
applications, mostly in the biomedical field. This review describes the synthesis of 2 …

Poly (2-oxazoline)-based stimulus-responsive (Co) polymers: An overview of their design, solution properties, surface-chemistries and applications

S Jana, M Uchman - Progress in Polymer Science, 2020‏ - Elsevier
Abstract Pseudopeptidic poly (2-oxazoline) s are a special class of bio-inspired polymers
with multiple applications, especially in the field of polymer therapeutics. Unsurprisingly …

Design and mechanisms of antifouling materials for surface plasmon resonance sensors

B Liu, X Liu, S Shi, R Huang, R Su, W Qi, Z He - Acta Biomaterialia, 2016‏ - Elsevier
Surface plasmon resonance (SPR) biosensors have many possible applications, but are
limited by sensor chip surface fouling, which blocks immobilization and specific binding by …

Polyoxazoline biointerfaces by surface grafting

G Morgese, EM Benetti - European Polymer Journal, 2017‏ - Elsevier
Functionalization of biomaterials by “grafting-to” of functional polymers represents a pivotal
strategy to hinder unspecific biological adhesion, provide functions to the modified …

Oligo (2-alkyl-2-oxazoline)-based graft copolymers for marine antifouling coatings

E Guazzelli, L Santarlasci, M Oliva, C Pretti… - European Polymer …, 2023‏ - Elsevier
Abstract Poly (ethylene glycol)(PEG)-based graft copolymers have been widely applied for
the modification of poly (dimethyl siloxane)(PDMS)-based coatings that resist marine …

Antibiofouling properties of plasma-deposited oxazoline-based thin films

AA Cavallaro, MN Macgregor-Ramiasa… - ACS applied materials …, 2016‏ - ACS Publications
Infections caused by the bacterial colonization of medical devices are a substantial problem
to patients and healthcare. Biopassive polyoxazoline coatings are attracting attention in the …

Folic Acid-Conjugated Brush Polymers Show Enhanced Blood–Brain Barrier Crossing in Static and Dynamic In Vitro Models Toward Brain Cancer Targeting Therapy

ZAI Mazrad, A Refaat, JP Morrow… - ACS Biomaterials …, 2024‏ - ACS Publications
Over the past decades, evidence has consistently shown that treatment of central nervous
system (CNS)-related disorders, including Alzheimer's disease, Parkinson's disease, stroke …

Molecular insights into site-specific interferon-α2a bioconjugates originated from PEG, LPG, and PEtOx

N Hauptstein, P Pouyan, J Kehrein, M Dirauf… - …, 2021‏ - ACS Publications
Conjugation of biologics with polymers modulates their pharmacokinetics, with polyethylene
glycol (PEG) as the gold standard. We compared alternative polymers and two types of …