Recent developments on other platinum metal complexes as target-specific anticancer therapeutics
Numerous biologically active metal complexes are reported for their unique features and
enhanced functions, particularly towards the inhibition of cancer progression. With the …
enhanced functions, particularly towards the inhibition of cancer progression. With the …
Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
Investigation into antiproliferative activity and apoptosis mechanism of new arene Ru (ii) carbazole-based hydrazone complexes
Ruthenium complexes with bioactive ligands are becoming promising substitutes for
platinum complexes due to their precise action against various cancers. In the present study …
platinum complexes due to their precise action against various cancers. In the present study …
Synthesis and Structure of Arene Ru(II) N∧O-Chelating Complexes: In Vitro Cytotoxicity and Cancer Cell Death Mechanism
A panel of six new structurally related organometallic arene Ru (II) complexes of general
composition [(η6-benzene) Ru (L) Cl](1–3) and [(η6-p-cymene) Ru (L) Cl](4–6)(L …
composition [(η6-benzene) Ru (L) Cl](1–3) and [(η6-p-cymene) Ru (L) Cl](4–6)(L …
Impact of aliphatic acyl and aromatic thioamide substituents on the anticancer activity of Ru (ii)-p-cymene complexes with acylthiourea ligands—in vitro and in vivo …
Six different acylthiourea ligands (L1–L6) and their corresponding Ru (II)-p-cymene
complexes (P1–P6) were designed to explore the structure–activity relationship of the …
complexes (P1–P6) were designed to explore the structure–activity relationship of the …
Transfer hydrogenation catalysis in cells
S Banerjee, PJ Sadler - RSC Chemical Biology, 2021 - pubs.rsc.org
Hydrogenation reactions in biology are usually carried out by enzymes with nicotinamide
adenine dinucleotide (NAD (P) H) or flavin mononucleotide (FAMH2)/flavinadenine …
adenine dinucleotide (NAD (P) H) or flavin mononucleotide (FAMH2)/flavinadenine …
Recent advances in anticancer ruthenium Schiff base complexes
S Parveen - Applied Organometallic Chemistry, 2020 - Wiley Online Library
Nowadays in cancer treatment, both metal complexes and organic molecules are being
widely used. Current years have seen a surge of interest in the application of organometallic …
widely used. Current years have seen a surge of interest in the application of organometallic …
Novel NHC-coordinated ruthenium (II) arene complexes achieve synergistic efficacy as safe and effective anticancer therapeutics
C Chen, C Xu, T Li, S Lu, F Luo, H Wang - European journal of medicinal …, 2020 - Elsevier
There is an urgent need for more effective, less toxic cancer therapy agents. Motivated by
this need, we synthesized a small panel of N-heterocyclic carbene (NHC)-coordinated …
this need, we synthesized a small panel of N-heterocyclic carbene (NHC)-coordinated …
Syntheses, structural characterization, and cytotoxicity assessment of novel Mn (II) and Zn (II) complexes of aroyl-hydrazone Schiff base Ligand
This work describes the syntheses, structural characterization, and biological profile of Mn
(II)-and Zn (II)-based complexes 1 and 2 derived from the aroyl-hydrazone Schiff base ligand …
(II)-and Zn (II)-based complexes 1 and 2 derived from the aroyl-hydrazone Schiff base ligand …
Selective coordination mode of acylthiourea ligands in half-sandwich Ru (II) complexes and their cytotoxic evaluation
BN Cunha, L Luna-Dulcey, AM Plutin… - Inorganic …, 2020 - ACS Publications
In this study, half-sandwich Ru (II) complexes containing acylthiourea ligands of the general
type [Ru (η6-p-cymene)(PPh3)(S) Cl] PF6 (1m–6m) and [Ru (η6-p-cymene)(PPh3)(S–O)] …
type [Ru (η6-p-cymene)(PPh3)(S) Cl] PF6 (1m–6m) and [Ru (η6-p-cymene)(PPh3)(S–O)] …